心血管疾病中的单核细胞亚群：生物标志物视角。

IF 5 2区医学 Q1 HEMATOLOGY

Thrombosis and haemostasis Pub Date : 2024-07-06 DOI:10.1055/a-2348-5697

Michael Hristov, Christian Weber

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引用次数: 0

摘要

内皮功能障碍、免疫反应失调和脂质积累是动脉粥样硬化发病和慢性发展的重要干扰因素。1 在这篇简明扼要的综述中，我们旨在重点介绍自 ESC 联合共识文件2 发表以来有关单核细胞亚群的最新基础研究和临床发现，并分析它们作为冠状动脉疾病（CAD）替代生物标志物的潜在相关性。

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Monocyte Subsets in Cardiovascular Disease: A Biomarker Perspective.

Endothelial dysfunctions together with a dysregulated immune response and lipid accumulation are important confounding factors in the onset and chronic development of atherosclerosis. Recently, a large body of data has emerged on the sequential involvement of different immune cell types, including monocytes, in the pathology of this disease. In this condensed review, we aim to highlight some of the recent basic research and clinical findings on monocyte subsets published since our joint European Society of Cardiology consensus document, and re-evaluate their potential relevance as surrogate biomarkers in coronary artery disease.

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来源期刊

Thrombosis and haemostasis 医学-外周血管病

CiteScore

11.90

自引率

9.00%

发文量

140

审稿时长

1 months

期刊介绍： Thrombosis and Haemostasis publishes reports on basic, translational and clinical research dedicated to novel results and highest quality in any area of thrombosis and haemostasis, vascular biology and medicine, inflammation and infection, platelet and leukocyte biology, from genetic, molecular & cellular studies, diagnostic, therapeutic & preventative studies to high-level translational and clinical research. The journal provides position and guideline papers, state-of-the-art papers, expert analysis and commentaries, and dedicated theme issues covering recent developments and key topics in the field.