Bassem Awada , Aref Zribi , Ahmad Ghoche , Hasan Al-Sayegh , Manyando Milupi , Boris Itkin , Khalid Al-Baimani , Jorge Abarca
{"title":"阿曼实体瘤癌症患者念珠菌血症中格拉布氏念珠菌占主导地位：一项回顾性研究","authors":"Bassem Awada , Aref Zribi , Ahmad Ghoche , Hasan Al-Sayegh , Manyando Milupi , Boris Itkin , Khalid Al-Baimani , Jorge Abarca","doi":"10.1016/j.ijregi.2024.100389","DOIUrl":null,"url":null,"abstract":"<div><h3>Objectives</h3><p><em>Candida</em> species frequently cause bloodstream infections; however, there is a lack of epidemiological studies on candidemia in Oman.</p></div><div><h3>Methods</h3><p>To address this, we conducted a retrospective study at Sultan Qaboos Comprehensive Cancer and Research Center from October 2021 to October 2023.</p></div><div><h3>Results</h3><p>Our study identified 27 episodes of candidemia among 26 patients with cancer, with an incidence of 4.9 per 1000 admissions. Non-<em>albicans Candida</em> (NAC) prevailed over <em>C. albicans</em> (70.37% vs 29.62%), with <em>C. glabrata</em> as the predominant NAC species (n = 10; 37%). The 30-day mortality rate was 40.7%, showing no significant difference between NAC and <em>C. albicans</em> but was notably higher in critically ill patients (<em>P</em> = 0.03).</p></div><div><h3>Conclusion</h3><p>In Oman, NAC surpasses <em>C. albicans</em> as a causative pathogen for candidemia with a high mortality rate.</p></div>","PeriodicalId":73335,"journal":{"name":"IJID regions","volume":null,"pages":null},"PeriodicalIF":1.5000,"publicationDate":"2024-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772707624000602/pdfft?md5=7388cdb4a5c402980e6fce7a42cc8b8f&pid=1-s2.0-S2772707624000602-main.pdf","citationCount":"0","resultStr":"{\"title\":\"Predominance of Candida glabrata in candidemia among patients with solid tumor cancer in Oman: A retrospective study\",\"authors\":\"Bassem Awada , Aref Zribi , Ahmad Ghoche , Hasan Al-Sayegh , Manyando Milupi , Boris Itkin , Khalid Al-Baimani , Jorge Abarca\",\"doi\":\"10.1016/j.ijregi.2024.100389\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Objectives</h3><p><em>Candida</em> species frequently cause bloodstream infections; however, there is a lack of epidemiological studies on candidemia in Oman.</p></div><div><h3>Methods</h3><p>To address this, we conducted a retrospective study at Sultan Qaboos Comprehensive Cancer and Research Center from October 2021 to October 2023.</p></div><div><h3>Results</h3><p>Our study identified 27 episodes of candidemia among 26 patients with cancer, with an incidence of 4.9 per 1000 admissions. Non-<em>albicans Candida</em> (NAC) prevailed over <em>C. albicans</em> (70.37% vs 29.62%), with <em>C. glabrata</em> as the predominant NAC species (n = 10; 37%). The 30-day mortality rate was 40.7%, showing no significant difference between NAC and <em>C. albicans</em> but was notably higher in critically ill patients (<em>P</em> = 0.03).</p></div><div><h3>Conclusion</h3><p>In Oman, NAC surpasses <em>C. albicans</em> as a causative pathogen for candidemia with a high mortality rate.</p></div>\",\"PeriodicalId\":73335,\"journal\":{\"name\":\"IJID regions\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.5000,\"publicationDate\":\"2024-06-15\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.sciencedirect.com/science/article/pii/S2772707624000602/pdfft?md5=7388cdb4a5c402980e6fce7a42cc8b8f&pid=1-s2.0-S2772707624000602-main.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"IJID regions\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2772707624000602\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"INFECTIOUS DISEASES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"IJID regions","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2772707624000602","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"INFECTIOUS DISEASES","Score":null,"Total":0}
Predominance of Candida glabrata in candidemia among patients with solid tumor cancer in Oman: A retrospective study
Objectives
Candida species frequently cause bloodstream infections; however, there is a lack of epidemiological studies on candidemia in Oman.
Methods
To address this, we conducted a retrospective study at Sultan Qaboos Comprehensive Cancer and Research Center from October 2021 to October 2023.
Results
Our study identified 27 episodes of candidemia among 26 patients with cancer, with an incidence of 4.9 per 1000 admissions. Non-albicans Candida (NAC) prevailed over C. albicans (70.37% vs 29.62%), with C. glabrata as the predominant NAC species (n = 10; 37%). The 30-day mortality rate was 40.7%, showing no significant difference between NAC and C. albicans but was notably higher in critically ill patients (P = 0.03).
Conclusion
In Oman, NAC surpasses C. albicans as a causative pathogen for candidemia with a high mortality rate.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
