不同程度的慢性鼻炎伴鼻息肉患者的冠状病毒病(COVID-19)发病率

E. Lyubimova, E. Savlevich, A. V. Zurochka, E. S. Mitrofanova, O. Kurbacheva
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All data about vaccination against coronavirus infection and confirmed COVID-19 episodes with an analysis of its severity were recorded,Results. 63 people had COVID-19 (63.64%, 62.5 ± 13.1 years), of which 62.5% people were vaccinated before infection. COVID-19 was mild in 84.1% (54.70 ± 13.83 years), moderate COVID-19 – in 12.7% (63.1 ± 15.38 years), and severe – in 3.2% (age – 40 years). 36% people (62.5 ± 13.1 years) did not infected with coronavirus. In group 1 mild COVID-19 was observed in 35.29%, moderate severity – in 5.88%. In group 2 all patients who had COVID-19 (87.5%) had mild course. In group 3 39.39% patients had mild COVID-19, 18.18% had moderate COVID-19. Severe COVID-19 was observed in 2 people from this group.Conclusions. COVID-19 was mild in most cases in CRSwNP patients. In 84.1% patients were treated as outpatients. 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To effect of COVID-19 on CRSwNP course in patients with different drug control degree.Materials and methods. 99 patients with bilateral CRSwNP (48 men, 51 women, 58.37 ± 14.43 years), were divided into 3 groups based on CRSwNP medical control degree for 5 years [17]. Group 1 (n = 34) – patients with mild CRSwNP received treatment according to treatment algorithm stages I and II. Group 2 (n = 32) – moderate severity CRSwNP, therapy corresponded to algorithm stage II or III. Group 3 (n = 33) – patients with severe CRSwNP received stage IV treatment 1 or more times. All data about vaccination against coronavirus infection and confirmed COVID-19 episodes with an analysis of its severity were recorded,Results. 63 people had COVID-19 (63.64%, 62.5 ± 13.1 years), of which 62.5% people were vaccinated before infection. 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摘要

引言慢性鼻炎伴鼻息肉(CRSwNP)的发病机制是基于局部免疫反应不足,额外的SARS-CoV-2感染可改变CRSwNP的病理过程。COVID-19对不同药物控制程度患者CRSwNP病程的影响。99例双侧CRSwNP患者(男48例,女51例,58.37±14.43岁),根据CRSwNP药物控制程度分为3组,为期5年[17]。第 1 组(n = 34)--轻度 CRSwNP 患者,根据治疗算法 I 和 II 阶段接受治疗。第 2 组(n = 32)--中度重度 CRSwNP,按照算法 II 或 III 阶段进行治疗。第 3 组(n = 33)--重度 CRSwNP 患者接受 1 次或多次第 IV 阶段治疗。记录了所有有关冠状病毒感染疫苗接种和确诊的 COVID-19 病例的数据,并对其严重程度进行了分析。63人感染了COVID-19(63.64%,62.5 ± 13.1岁),其中62.5%的人在感染前接种过疫苗。84.1%(54.70 ± 13.83 岁)的人感染了轻度 COVID-19,12.7%(63.1 ± 15.38 岁)的人感染了中度 COVID-19,3.2%(40 岁)的人感染了重度 COVID-19。36%的人(62.5 ± 13.1 岁)没有感染冠状病毒。在第 1 组中,有 35.29% 的人患有轻度 COVID-19,5.88% 的人患有中度。在第 2 组中,所有 COVID-19 患者(87.5%)的病程均为轻度。在第 3 组中,39.39% 的患者有轻度 COVID-19,18.18% 的患者有中度 COVID-19。结论:COVID-19 在大多数患者中为轻度。大多数 CRSwNP 患者的 COVID-19 为轻度。84.1%的患者接受了门诊治疗。CRSwNP 患者由于主诉嗅觉减退和怀疑感染冠状病毒,需要频繁进行拭子检查以检测 SARS-CoV-2 RNA。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Incidence of coronavirus disease (COVID-19) in patients with different degrees of chronic rhinosinusitis with nasal polyps
Introduction. Chronic rhinosinusitis with nasal polyps (CRSwNP) pathogenesis is based on inadequate local immune response, additional SARS-CoV-2 infection can alter CRSwNP pathological process.Aim. To effect of COVID-19 on CRSwNP course in patients with different drug control degree.Materials and methods. 99 patients with bilateral CRSwNP (48 men, 51 women, 58.37 ± 14.43 years), were divided into 3 groups based on CRSwNP medical control degree for 5 years [17]. Group 1 (n = 34) – patients with mild CRSwNP received treatment according to treatment algorithm stages I and II. Group 2 (n = 32) – moderate severity CRSwNP, therapy corresponded to algorithm stage II or III. Group 3 (n = 33) – patients with severe CRSwNP received stage IV treatment 1 or more times. All data about vaccination against coronavirus infection and confirmed COVID-19 episodes with an analysis of its severity were recorded,Results. 63 people had COVID-19 (63.64%, 62.5 ± 13.1 years), of which 62.5% people were vaccinated before infection. COVID-19 was mild in 84.1% (54.70 ± 13.83 years), moderate COVID-19 – in 12.7% (63.1 ± 15.38 years), and severe – in 3.2% (age – 40 years). 36% people (62.5 ± 13.1 years) did not infected with coronavirus. In group 1 mild COVID-19 was observed in 35.29%, moderate severity – in 5.88%. In group 2 all patients who had COVID-19 (87.5%) had mild course. In group 3 39.39% patients had mild COVID-19, 18.18% had moderate COVID-19. Severe COVID-19 was observed in 2 people from this group.Conclusions. COVID-19 was mild in most cases in CRSwNP patients. In 84.1% patients were treated as outpatients. CRSwNP patients had frequent swabs to detect SARS-CoV-2 RNA due to complaints of hyposmia and raised coronavirus infection suspicion.
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