Immune system triggers as a factor for the formation of foreign body granuloma after hyaluronic acid fillers treatment.

Injections of hyaluronic acid dermal fillers are minimally invasive cosmetic procedures that in general are considered safe. However, a lot of complications have been reported for the last couple of years. The formation of foreign body granuloma is a rare side effect which usually happens weeks to months after the injection of soft tissue fillers and is one of the most challenging when it comes to management. This study aims to report a case of foreign body granuloma formation after full face treatment with 12 ml of hyaluronic dermal fillers. A short overview of the main factors influencing granuloma formation and a treatment protocol are also presented.