Yaohua Wei, Feng Shen, Huidong Song, Ruifang Zhao, Weiyue Feng, Yue Pan, Xiaobo Li, Huanling Yu, Giuseppe Familiari, Michela Relucenti, Michael Aschner, Hanping Shi, Rui Chen, Guangjun Nie, Hanqing Chen
{"title":"肠道微生物群靶向纳米药物治疗结直肠癌的挑战与机遇","authors":"Yaohua Wei, Feng Shen, Huidong Song, Ruifang Zhao, Weiyue Feng, Yue Pan, Xiaobo Li, Huanling Yu, Giuseppe Familiari, Michela Relucenti, Michael Aschner, Hanping Shi, Rui Chen, Guangjun Nie, Hanqing Chen","doi":"10.1002/imt2.213","DOIUrl":null,"url":null,"abstract":"<p>The gut microbiota is an integral component of the colorectal cancer (CRC) microenvironment and is intimately associated with CRC initiation, progression, and therapeutic outcomes. We reviewed recent advancements in utilizing nanotechnology for modulating gut microbiota, discussing strategies and the mechanisms underlying their design. For future nanomedicine design, we propose a 5I principle for individualized nanomedicine in CRC management.\n <figure>\n <div><picture>\n <source></source></picture><p></p>\n </div>\n </figure></p>","PeriodicalId":73342,"journal":{"name":"iMeta","volume":"3 4","pages":""},"PeriodicalIF":23.7000,"publicationDate":"2024-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/imt2.213","citationCount":"0","resultStr":"{\"title\":\"The challenge and opportunity of gut microbiota-targeted nanomedicine for colorectal cancer therapy\",\"authors\":\"Yaohua Wei, Feng Shen, Huidong Song, Ruifang Zhao, Weiyue Feng, Yue Pan, Xiaobo Li, Huanling Yu, Giuseppe Familiari, Michela Relucenti, Michael Aschner, Hanping Shi, Rui Chen, Guangjun Nie, Hanqing Chen\",\"doi\":\"10.1002/imt2.213\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>The gut microbiota is an integral component of the colorectal cancer (CRC) microenvironment and is intimately associated with CRC initiation, progression, and therapeutic outcomes. We reviewed recent advancements in utilizing nanotechnology for modulating gut microbiota, discussing strategies and the mechanisms underlying their design. For future nanomedicine design, we propose a 5I principle for individualized nanomedicine in CRC management.\\n <figure>\\n <div><picture>\\n <source></source></picture><p></p>\\n </div>\\n </figure></p>\",\"PeriodicalId\":73342,\"journal\":{\"name\":\"iMeta\",\"volume\":\"3 4\",\"pages\":\"\"},\"PeriodicalIF\":23.7000,\"publicationDate\":\"2024-06-10\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://onlinelibrary.wiley.com/doi/epdf/10.1002/imt2.213\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"iMeta\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1002/imt2.213\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"MICROBIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"iMeta","FirstCategoryId":"1085","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/imt2.213","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"MICROBIOLOGY","Score":null,"Total":0}
The challenge and opportunity of gut microbiota-targeted nanomedicine for colorectal cancer therapy
The gut microbiota is an integral component of the colorectal cancer (CRC) microenvironment and is intimately associated with CRC initiation, progression, and therapeutic outcomes. We reviewed recent advancements in utilizing nanotechnology for modulating gut microbiota, discussing strategies and the mechanisms underlying their design. For future nanomedicine design, we propose a 5I principle for individualized nanomedicine in CRC management.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
