吸食鸦片对产后脐带血和产妇血液中炎症因子的影响：新生儿并发症的潜在诱因

IF 1.2 4区社会学 Q4 SUBSTANCE ABUSE

Journal of Drug Issues Pub Date : 2024-06-10 DOI:10.1177/00220426241259374

S. Khayat, H. Fanaei, Farideh Riki, Shahindokht Navabi Rigi, Ebrahim Alijani

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引用次数: 0

摘要

怀孕期间吸食鸦片会对免疫系统的活动和妊娠结果产生重大影响。一项研究将吸食鸦片的孕妇与健康孕妇进行了比较。研究人员在孕妇分娩后立即从母体静脉和脐带抽取血液样本，以测量炎症标志物的浓度。结果显示，与对照组相比，鸦片成瘾组孕妇和脐带血样本中的 IL-6、IL-10、CRP、C3 和 C4 水平明显更高。此外，鸦片成瘾组的不良妊娠结局，如入住新生儿重症监护室、新生儿死亡和低Apgar评分更为普遍。这些研究结果表明，孕期吸食鸦片成瘾会导致产后炎症，并对妊娠结局产生负面影响。必须解决鸦片成瘾问题，并为孕妇提供适当的支持和治疗，以改善妊娠结局，降低并发症风险。

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The Impact of Opium Consumption on Inflammatory Factors in Umbilical Cord Blood and Maternal Blood Postpartum: A Potential Contributor to Neonatal Complications

Opium addiction during pregnancy can have significant effects on the activity of the immune system as well as on pregnancy outcomes. A study was conducted comparing opium-addicted pregnant women to healthy pregnant women. Blood samples were taken from the maternal vein and umbilical cord immediately after delivery to measure concentrations of inflammatory markers. The results showed that the opium-addicted group had significantly higher levels of IL-6, IL-10, CRP, C3, and C4 in both maternal and cord blood samples compared to the control group. Additionally, adverse pregnancy outcomes such as NICU admissions, neonatal deaths, and low Apgar scores were more prevalent in the opium-addicted group. These findings suggest that opium addiction during pregnancy can lead to postpartum inflammation and negatively impact pregnancy outcomes. It is important to address opium addiction and provide appropriate support and treatment to pregnant women to improve pregnancy outcomes and reduce the risk of complications.

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来源期刊

Journal of Drug Issues SUBSTANCE ABUSE-

CiteScore

3.00

自引率

11.80%

发文量

期刊介绍： The Journal of Drug Issues (JDI) was incorporated as a nonprofit entity in the State of Florida in 1971. In 1996, JDI was transferred to the Florida State University College of Criminology and Criminal Justice, and the Richard L. Rachin Endowment was established to support its continued publication. Since its inception, JDI has been dedicated to providing a professional and scholarly forum centered on the national and international problems associated with drugs, especially illicit drugs. It is a refereed publication with international contributors and subscribers. As a leader in its field, JDI is an instrument widely used by research scholars, public policy analysts, and those involved in the day-to-day struggle against the problem of drug abuse.