An Effective Treatment for Progressive Keratoconus with Two-Year Outcomes: Accelerated Epithelium-on Corneal Cross-Linking

Purpose: Corneal collagen cross-linking is a surgical technique for progressive keratoconus. There are several technical modifications with varying clinical outcomes. This study aimed to evaluate the long-term outcomes of the accelerated epithelium-on collagen cross-linking. Design & Methods: A retrospective study was performed on progressive keratoconus patients treated via the accelerated epithelium-on collagen cross-linking who completed the 24th-month follow-up. We included 111 eyes of 77 patients. Clinical variables, including visual acuity, aberrometry, topographic measurements, and refractive outcomes, were evaluated at the postoperative 12th and 24th months. Results: There was a significant improvement in postoperative visual acuity in 50.4% of the patients (p