O B Belousova, A N Konovalov, I A Savin, T M Birg, K N Lapteva, D I Pitskhelauri, Sh U Kadyrov, Yu G Sidneva, E A Khhukhlaeva
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[Recovery of consciousness under therapy with benzodiazepines. A case report and literature review].
Background: Treatment of patients with prolonged and permanent disturbance of consciousness is still an extremely difficult problem. Nowadays, management is based on pathophysiological and molecular mechanisms of impaired consciousness. Several electrophysiological and pharmacological methods were proposed to restore consciousness in appropriate patients.
Objective: We present recovery of clear consciousness under therapy with phenazepam and literature review devoted to therapy of these disorders.
Results and conclusion: This case confirms available data on drug neuromodulation in complex treatment of patients with prolonged impairment of consciousness and substantiates the need for individual multimodal assessment of structural and functional disorders in prolonged and chronic impairment of consciousness for adequate therapy.
期刊介绍:
Scientific and practical peer-reviewed journal. This publication covers the theoretical, practical and organizational problems of modern neurosurgery, the latest advances in the treatment of various diseases of the central and peripheral nervous system. Founded in 1937. English version of the journal translates from Russian version since #1/2013.