光子计数 CT 进入人工耳蜗植入领域:与血管造影 DynaCT 和传统多层 CT 的比较。

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY
Kristen Rak, Bjoern Spahn, Franz-Tassilo Müller-Graff, Jonas Engert, Johannes Voelker, Stephan Hackenberg, Rudolf Hagen, Bernhard Petritsch, Jan-Peter Grunz, Thorsten Bley, Tilmann Neun, Henner Huflage
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引用次数: 0

摘要

导言:人工耳蜗导管长度(CDL)测量在个体化人工耳蜗植入(CI)手术中起着重要作用,它涉及 CI 电极载体的个体化选择和植入,以及基于解剖的高效术后验配过程。术前颞骨 CT 扫描的详细程度取决于对 CDL 测量和 CI 电极接触位置确定有重大影响的成像模式。本研究旨在评估光子计数 CT(PCCT)围术期 CDL 测量和电极接触确定的准确性:方法:使用第一代 PCCT 检查了十个人体新鲜冷冻的岩骨标本。使用的临床适用辐射剂量为 27.1 mGy。在插入 CI 之前和之后进行扫描。术后使用耳科规划软件和三维曲面多平面重建对 CDL 进行了测量。电极接触位置的调查由两名观察员分别进行。测量结果与传统的多层 CT 和二次重建的高分辨率平板容积 CT 进行了比较:结果:PCCT 图像的术前和术后 CDL 测量结果与高分辨率平板容积 CT 没有明显差异。术后 CI 电极接触测定也与基于平板 CT 的评估一样精确。在观察者间变异性方面,PCCT 和平板容积 CT 相当:结论:使用 PCCT 测量 CDL 与使用二次重建的平板容积 CT 相当。与传统的多层 CT 扫描仪相比,PCCT 能够高度精确地确定术后 CI 电极的接触情况。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The Photon-Counting CT Enters the Field of Cochlear Implantation: Comparison to Angiography DynaCT and Conventional Multislice CT.

Introduction: Cochlear duct length (CDL) measurement plays a role in the context of individualized cochlear implant (CI) surgery regarding an individualized selection and implantation of the CI electrode carrier and an efficient postoperative anatomy-based fitting process. The level of detail of the preoperative temporal bone CT scan depends on the imaging modality with major impact on CDL measurements and CI electrode contact position determination. The aim of this study was to evaluate the accuracy of perioperative CDL measurements and electrode contact determination in photon-counting CT (PCCT).

Methods: Ten human fresh-frozen petrous bone specimens were examined with a first-generation PCCT. A clinically applicable radiation dose of 27.1 mGy was used. Scans were acquired before and after CI insertion. Postoperative measurement of the CDL was conducted using an otological planning software and 3D-curved multiplanar reconstruction. Investigation of electrode contact position was performed by two respective observers. Measurements were compared with a conventional multislice CT and to a high-resolution flat-panel volume CT with secondary reconstructions.

Results: Pre- and postoperative CDL measurements in PCCT images showed no significant difference to high-resolution flat-panel volume CT. Postoperative CI electrode contact determination was also as precise as the flat-panel CT-based assessment. PCCT and flat-panel volume CT were equivalent concerning interobserver variability.

Conclusion: CDL measurement with PCCT was equivalent to flat-panel volume CT with secondary reconstructions. PCCT enabled highly precise postoperative CI electrode contact determination with substantial advantages over conventional multislice CT scanners.

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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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