肥大细胞2 型炎症的杰纳斯

IF 25.5 1区医学 Q1 IMMUNOLOGY

Immunity Pub Date : 2024-06-11 DOI:10.1016/j.immuni.2024.05.011

Johanna Kotrba, Anne Dudeck

引用次数: 0

摘要

肥大细胞（MC）是第二型免疫的效应因子，因其在过敏症中的有害作用而众所周知。在本期《免疫》杂志上，Alhallak 等人发现了肥大细胞对由前列腺素 E2（PGE2）驱动的可溶性 ST2 引起的免疫反应的保护作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Mast cells: The Janus of type 2 inflammation

Mast cells (MCs) are effectors in type 2 immunity, well known for their detrimental roles in allergy. In this issue of Immunity, Alhallak et al. now identify a protective role of MCs against exacerbated immune responses mediated by prostaglandin E₂ (PGE₂)-driven soluble ST2.

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来源期刊

Immunity 医学-免疫学

CiteScore

49.40

自引率

2.20%

发文量

205

审稿时长

6 months

期刊介绍： Immunity is a publication that focuses on publishing significant advancements in research related to immunology. We encourage the submission of studies that offer groundbreaking immunological discoveries, whether at the molecular, cellular, or whole organism level. Topics of interest encompass a wide range, such as cancer, infectious diseases, neuroimmunology, autoimmune diseases, allergies, mucosal immunity, metabolic diseases, and homeostasis.