间接比较用于 EUS 引导下胆道和胆囊引流的各种管腔贴壁金属支架：系统回顾和荟萃分析。

IF 6.7 1区医学 Q1 GASTROENTEROLOGY & HEPATOLOGY

Gastrointestinal endoscopy Pub Date : 2024-11-01 DOI:10.1016/j.gie.2024.05.024

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引用次数: 0

摘要

背景和目的：评估内镜超声引导下胆道引流术（EUS-BD）或胆囊引流术（EUS-GB）使用管腔贴合金属支架（LAMS）的研究显示，LAMS类型不同，结果也不同。我们对现有数据进行了荟萃分析：我们在多个在线数据库中搜索了使用 LAMS（AXIOS 或 SPAXUS）进行 EUS-BD 和 EUS-GB 的研究。相关结果包括技术成功率、临床成功率和不良事件。计算了汇总比例和95%置信区间（CI）：结果：共纳入了 18 项观察性研究：其中 11 项研究针对 AXIOS 支架（433 名患者，平均年龄 72 岁，54% 为男性），7 项针对 SPAXUS 支架（242 名患者，平均年龄 74 岁，50% 为男性）。AXIOS支架（EUS-BD和EUS-GB）的汇总结果分别为：技术成功率（96.2%和96.2%）、临床成功率（92.8%和92.7%）、总不良事件（10.1%和23.6%）和出血（3.7%和4.8%）。SPAXUS支架（EUS-BD和EUS-GB）的汇总结果分别为：技术成功率（93.8%和95.9%）、临床成功率（90.1%和94.2%）、不良事件总数（12.6%和9.5%）以及出血（3.1%和1.8%）：结论：AXIOS支架和SPAXUS支架的总体技术和临床成功率相似。在 EUS-GB 过程中，23.6% 的患者（AXIOS 支架）和 9.5% 的患者（SPAXUS 支架）发生了不良事件。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Indirect comparison of various lumen-apposing metal stents for EUS-guided biliary and gallbladder drainage: a systematic review and meta-analysis

Background and Aims

Studies assessing EUS-guided biliary drainage (EUS-BD) or gallbladder drainage (EUS-GB) using lumen-apposing metal stents (LAMSs) have shown variable results based on the type of LAMS. We performed a meta-analysis of the available data.

Methods

Multiple online databases were searched for studies using LAMSs (Axios [Boston Scientific, Marlborough, Mass, USA] or Spaxus [Taewoong Medical Co, Gimpo, Korea]) for EUS-BD and EUS-GB. The outcomes of interest were technical success, clinical success, and adverse events. Pooled proportions along with 95% confidence intervals were calculated.

Results

A total of 18 observational studies were included: 11 for the Axios stent (433 patients; mean age, 72 years; 54% male) and 7 for the Spaxus stent (242 patients; mean age, 74 years; 50% male). The respective pooled outcomes for the Axios stent (EUS-BD and EUS-GB, respectively) were technical success, 96.2% and 96.2%; clinical success, 92.8% and 92.7%; total adverse events, 10.1% and 23.6%; and bleeding, 3.7% and 4.8%. The respective pooled outcomes for the Spaxus stent (EUS-BD and EUS-GB, respectively) were technical success, 93.8% and 95.9%; clinical success, 90.1% and 94.2%; total adverse events, 12.6% and 9.5%; and bleeding, 3.1% and 1.8%.

Conclusions

Axios and Spaxus stents demonstrate similar pooled technical and clinical success rates. Adverse events occurred in 23.6% of patients (Axios stent) and 9.5% of patients (Spaxus stent) during EUS-GB.

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来源期刊

Gastrointestinal endoscopy 医学-胃肠肝病学

CiteScore

10.30

自引率

7.80%

发文量

1441

审稿时长

38 days

期刊介绍： Gastrointestinal Endoscopy is a journal publishing original, peer-reviewed articles on endoscopic procedures for studying, diagnosing, and treating digestive diseases. It covers outcomes research, prospective studies, and controlled trials of new endoscopic instruments and treatment methods. The online features include full-text articles, video and audio clips, and MEDLINE links. The journal serves as an international forum for the latest developments in the specialty, offering challenging reports from authorities worldwide. It also publishes abstracts of significant articles from other clinical publications, accompanied by expert commentaries.