通过 2-甲酰基苯硼酸与酰胺的 Chan-Evans-Lam 偶联合成 2-芳基喹唑啉类化合物

IF 1.4 4区化学 Q3 CHEMISTRY, ORGANIC

Chemistry of Heterocyclic Compounds Pub Date : 2024-06-05 DOI:10.1007/s10593-024-03314-2

Vitalii V. Solomin, Darija Zaharova, Aigars Jirgensons

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引用次数: 0

摘要

本文介绍了一种合成 2-芳基喹唑啉的方法，该方法涉及 2-甲酰基苯硼酸与胺的 Chan-Evans-Lam 偶联。该反应在温和的条件下进行，与官能团的范围相适应，并通过使用廉价的催化剂和试剂实现成本效益。所介绍的 2-芳基喹唑啉的合成方法适用于 2-甲酰基苯硼酸和脒。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Synthesis of 2-arylquinazolines by Chan–Evans–Lam coupling of 2-formylphenylboronic acids with amidines

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Synthesis of 2-arylquinazolines by Chan–Evans–Lam coupling of 2-formylphenylboronic acids with amidines

A method for the synthesis of 2-arylquinazolines is described which involves Chan–Evans–Lam coupling of 2-formylphenylboronic acids with amidines. The reaction is performed at mild conditions compatible with the range of functional groups and is cost-efficient, provided by usage of inexpensive catalyst and reagents. The synthesis method of 2-arylquinazolines presented is of with scope in both 2-formylphenylboronic acids and amidines.

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来源期刊

Chemistry of Heterocyclic Compounds 化学-有机化学

CiteScore

2.90

自引率

13.30%

发文量

审稿时长

1 months

期刊介绍： The international journal Chemistry of Heterocyclic Compounds publishes original papers, short communications, reviews, and mini-reviews dealing with problems in the field of heterocyclic chemistry in Russian and English. The Journal also publishes reviews and annotations on new books and brief reports on conferences in the field of heterocyclic chemistry, as well as commemoratives dedicated to prominent heterocyclic chemists.