Correction: impact of sex differences on thrombin‑induced hydrocephalus and white matter injury: the role of neutrophils

Correction: fluids barriers CNS 18, 38 (2021)

https://doi.org/10.1186/s12987-021-00273-0

The original publication of this article [1] should have stated that one image in Fig. 1A had been published previously.

This is corrected in the legend below in bold and the original publication has been updated.

Figure 1 Intracerebroventricular injection of thrombin induced severe ventricular dilation, ventricular wall damage, and neutrophil infiltration in male rats. A T2 weighted MRI showing ventricular volume at 24 h after ICV injection of 50 µl of saline or thrombin (3U) in male rats. The bottom left image of this panel has been published previously [2]. B Representative images of H&E staining showing ependymal denudation and rupture (arrows) at 24 h in the thrombin (3U) but not the saline group. Scale bar = 50 mm. C Representative H&E and myeloperoxidase (MPO) staining of the choroid plexus and ventricle wall 24 h after thrombin or saline injection. Note the neutrophil infiltration into the choroid plexus and the ventricular wall damage in the thrombin injection group. Lower magnification, scale bar = 50 μm; higher magnification, scale bar = 10 μm.

1. Peng K, Koduri S, Xia F, et al. Impact of sex differences on thrombin-induced hydrocephalus and white matter injury: the role of neutrophils. Fluids Barriers CNS. 2021;18:38. https://doi.org/10.1186/s12987-021-00273-0

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2. Wan Y, Hua Y, Garton HJL, Novakovic N, Keep RF, Xi G. Activation of Epiplexus macrophages in hydrocephalus caused by subarachnoid hemorrhage and thrombin. CNS Neurosci Ther. 2019;25(10):1134–41.

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Authors and Affiliations

1. Department of Neurosurgery, University of Michigan, R5018 Biomedical Science Research Building, 109 Zina Pitcher Place, Ann Arbor, MI, 48109‑2200, USA

   Kang Peng, Sravanthi Koduri, Fan Xia, Feng Gao, Ya Hua, Richard F. Keep & Guohua Xi

2. Department of Neurosurgery, Xiangya Hospital, Central South University, Changsha, China

   Kang Peng

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6. Richard F. KeepView author publications

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Correspondence to Guohua Xi.

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Peng, K., Koduri, S., Xia, F. et al. Correction: impact of sex differences on thrombin‑induced hydrocephalus and white matter injury: the role of neutrophils. Fluids Barriers CNS 21, 50 (2024). https://doi.org/10.1186/s12987-024-00551-7

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• Published: 05 June 2024

• DOI: https://doi.org/10.1186/s12987-024-00551-7

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