美洲驼鼻窦软骨肉瘤。

IF 1.2 3区 农林科学 Q3 VETERINARY SCIENCES
Arthur Cheng, Katharine Horzmann, Ji-Hang Yin, Patricia Titos, Jenna E Bayne, Rachel Neto
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引用次数: 0

摘要

一只 14 岁的完整雌性骆驼(Lama glama)因右上颌肿胀 3 个月而前来接受评估。临床表现为轻度流鼻涕、右眼异常后退和中度牙龈疾病。上颌骨肿块的切口活检显示,多形性、有丝分裂活跃的肿瘤性纺锤至星状细胞杂乱无章地排列在空隙中,嵌入大量软骨基质中。鉴于预后不良,患者被实施了安乐死。尸检和头部切片发现了一个巨大的白色坚实肿块,肿块向右眶下区域扩展,一直延伸到上颌骨,侵蚀了右侧鼻螺纹和同侧颧骨。综合尸体解剖、细胞学和原发肿块的组织病理学检查结果,支持鼻窦软骨肉瘤的诊断。据我们所知,这种疾病以前从未在该物种中报道过,应将其作为新世界驼科动物面部畸形的鉴别诊断。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Sinonasal chondrosarcoma in a llama.

A 14-y-old intact female llama (Lama glama) was presented for evaluation of a right maxillary swelling of 3-mo duration. Clinically, the animal had mild nasal discharge, abnormal retropulsion of the right eye, and moderate gingival disease. An incisional biopsy of the maxillary mass revealed pleomorphic and mitotically active neoplastic spindle-to-stellate cells organized in haphazard lacunae embedded in abundant chondroid matrix. Given the poor prognosis, euthanasia was elected. Postmortem examination and sectioning of the head exposed a large solid, white, firm mass that vastly expanded the right infraorbital region, extending to the maxilla, effacing the right nasal conchae and ipsilateral zygomatic bone. Collectively, postmortem dissection, cytology, and histopathology of the primary mass supported a diagnosis of sinonasal chondrosarcoma. To our knowledge, this entity had not been reported previously in this species and should be considered a differential for facial deformities in New World camelids.

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来源期刊
CiteScore
3.00
自引率
6.70%
发文量
127
审稿时长
6-16 weeks
期刊介绍: The Journal of Veterinary Diagnostic Investigation (J Vet Diagn Invest) is an international peer-reviewed journal published bimonthly in English by the American Association of Veterinary Laboratory Diagnosticians (AAVLD). JVDI is devoted to all aspects of veterinary laboratory diagnostic science including the major disciplines of anatomic pathology, bacteriology/mycology, clinical pathology, epidemiology, immunology, laboratory information management, molecular biology, parasitology, public health, toxicology, and virology.
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