自发性蛛网膜下腔出血的紧急处理。

Q1 Medicine
Soojin Park
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引用次数: 0

摘要

目的:自发性蛛网膜下腔出血(SAH)具有很高的发病率和死亡率,对这种疾病的紧急处理会对患者的预后产生很大影响。本文旨在对 SAH 的紧急处理进行实用性概述:最新进展:最近的试验对以下方面的实践产生了影响:抗纤维蛋白溶解剂的使用、动脉瘤固定的时机、脑水肿的识别和避免灌注下限的重点,以及延迟性脑缺血的检测和预防。正如美国心脏协会/美国卒中协会和神经重症监护协会于 2023 年发布的两份更新指南所证明的,SAH 的急性期管理大部分都可以规范化。然而,证据上的差距导致重症监护管理的某些方面出现临床等效:在急性期管理中,当务之急是区分 SAH 的病因,并采取关键的紧急措施,包括血压管理和凝血病逆转。SAH 的重症监护管理与其他急性脑损伤相似,但需要检测和治疗延迟性脑缺血。检测和治疗延迟性脑缺血的策略受到意识障碍的限制,可通过监测和成像技术加以强化。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Emergent Management of Spontaneous Subarachnoid Hemorrhage.

Objective: Spontaneous subarachnoid hemorrhage (SAH) carries high morbidity and mortality rates, and the emergent management of this disease can make a large impact on patient outcome. The purpose of this article is to provide a pragmatic overview of the emergent management of SAH.

Latest developments: Recent trials have influenced practice around the use of antifibrinolytics, the timing of aneurysm securement, the recognition of cerebral edema and focus on avoiding a lower limit of perfusion, and the detection and prevention of delayed cerebral ischemia. Much of the acute management of SAH can be protocolized, as demonstrated by two updated guidelines published by the American Heart Association/American Stroke Association and the Neurocritical Care Society in 2023. However, the gaps in evidence lead to clinical equipoise in some aspects of critical care management.

Essential points: In acute management, there is an urgency to differentiate the etiology of SAH and take key emergent actions including blood pressure management and coagulopathy reversal. The critical care management of SAH is similar to that of other acute brain injuries, with the addition of detecting and treating delayed cerebral ischemia. Strategies for the detection and treatment of delayed cerebral ischemia are limited by disordered consciousness and may be augmented by monitoring and imaging technology.

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来源期刊
CiteScore
5.80
自引率
0.00%
发文量
175
期刊介绍: Continue your professional development on your own schedule with Continuum: Lifelong Learning in Neurology®, the American Academy of Neurology" self-study continuing medical education publication. Six times a year you"ll learn from neurology"s experts in a convenient format for home or office. Each issue includes diagnostic and treatment outlines, clinical case studies, a topic-relevant ethics case, detailed patient management problem, and a multiple-choice self-assessment examination.
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