Utilizing Large Language Models to Generate Synthetic Data to Increase the Performance of BERT-Based Neural Networks.

An important problem impacting healthcare is the lack of available experts. Machine learning (ML) models may help resolve this by aiding in screening and diagnosing patients. However, creating large, representative datasets to train models is expensive. We evaluated large language models (LLMs) for data creation. Using Autism Spectrum Disorders (ASD), we prompted GPT-3.5 and GPT-4 to generate 4,200 synthetic examples of behaviors to augment existing medical observations. Our goal is to label behaviors corresponding to autism criteria and improve model accuracy with synthetic training data. We used a BERT classifier pretrained on biomedical literature to assess differences in performance between models. A random sample (N=140) from the LLM-generated data was also evaluated by a clinician and found to contain 83% correct behavioral example-label pairs. Augmenting the dataset increased recall by 13% but decreased precision by 16%. Future work will investigate how different synthetic data characteristics affect ML outcomes.