唾液,人体的分子反映?对诊断和治疗的意义。

IF 4.1 Q2 CELL BIOLOGY
Cell Stress Pub Date : 2024-05-27 eCollection Date: 2024-01-01 DOI:10.15698/cst2024.05.297
Vincent Géli, Norbert Nabet
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引用次数: 0

摘要

对于许多疾病,尤其是癌症,早期诊断可以提供更广泛的治疗方法和更好的疾病管理。这促使诊断程序不断改进,其中最常见的是基于组织活检或血液样本的诊断程序。其他生物液体也被用于诊断疾病,其中唾液具有许多优势,因为它可以以相对较低的成本从大量人群中非侵入性地收集。唾液内容能在多大程度上揭示距离口腔较远的肿瘤的存在,以及从唾液中获得的分子信息可用于确定诊断,这些都是当前的问题。本综述主要侧重于唾液的内容,并说明唾液如何有可能为癌症或子宫内膜异位症等病症提供早期诊断来源。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Saliva, a molecular reflection of the human body? Implications for diagnosis and treatment.

For many diseases, and cancer in particular, early diagnosis allows a wider range of therapies and a better disease management. This has led to improvements in diagnostic procedures, most often based on tissue biopsies or blood samples. Other biological fluids have been used to diagnose disease, and among them saliva offers a number of advantages because it can be collected non-invasively from large populations at relatively low cost. To what extent might saliva content reveal the presence of a tumour located at a distance from the oral cavity and the molecular information obtained from saliva be used to establish a diagnosis are current questions. This review focuses primarily on the content of saliva and shows how it potentially offers a source of diagnosis, possibly at an early stage, for pathologies such as cancers or endometriosis.

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来源期刊
Cell Stress
Cell Stress Biochemistry, Genetics and Molecular Biology-Biochemistry, Genetics and Molecular Biology (miscellaneous)
CiteScore
13.50
自引率
0.00%
发文量
21
审稿时长
15 weeks
期刊介绍: Cell Stress is an open-access, peer-reviewed journal that is dedicated to publishing highly relevant research in the field of cellular pathology. The journal focuses on advancing our understanding of the molecular, mechanistic, phenotypic, and other critical aspects that underpin cellular dysfunction and disease. It specifically aims to foster cell biology research that is applicable to a range of significant human diseases, including neurodegenerative disorders, myopathies, mitochondriopathies, infectious diseases, cancer, and pathological aging. The scope of Cell Stress is broad, welcoming submissions that represent a spectrum of research from fundamental to translational and clinical studies. The journal is a valuable resource for scientists, educators, and policymakers worldwide, as well as for any individual with an interest in cellular pathology. It serves as a platform for the dissemination of research findings that are instrumental in the investigation, classification, diagnosis, and therapeutic management of major diseases. By being open-access, Cell Stress ensures that its content is freely available to a global audience, thereby promoting international scientific collaboration and accelerating the exchange of knowledge within the research community.
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