Máté Szabó, Gabriella Gárdián, László Szpisjak, András Salamon, Tamás Gábor, Péter Klivényi, Dénes Zádori
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引用次数: 0
摘要
背景:由于颈性肌张力障碍(CD)的表现多种多样,因此采用个性化方法实现治疗目标是非常有利的:方法:38 名定期接受肉毒杆菌神经毒素(BoNT)治疗的 CD 患者参与了本次探索性观察试点研究。GAS包括运动、疼痛、残疾和精神特征等领域,通过计算初始GAS T-scores来设定个体化目标。在至少 4 个 BoNT 注射周期后,重新评估患者是否达到了预设目标:结果:患者的初始 GAS T 评分(中位数:36.9,范围:22.8-40)明显改善(P 结论:患者的初始 GAS T 评分(中位数:36.9,范围:22.8-40)明显改善:GAS在CD患者中的适用性已得到证实,但还需要进一步的大规模研究来完善这一创新方法。
The Application of Goal Attainment Scaling in Cervical Dystonia - An Exploratory Observational Pilot Study.
Background: Due to its heterogeneous manifestation an individualized approach to reach therapeutic goals in cervical dystonia (CD) is advantageous.
Objectives: The aim of the current study was to adapt goal attainment scaling (GAS) to drive the management of CD.
Methods: 38 patients with CD, regularly treated with botulinum neurotoxin (BoNT), were involved in the current exploratory observational pilot study. GAS, including domains of motor, pain, disability, and psychiatric features, was applied to set up individualized goals with the calculation of initial GAS T-scores. Following at least 4 BoNT injection cycles, patients were reassessed whether they reached the pre-set goals.
Results: The initial GAS T-scores (median: 36.9, range: 22.8-40) significantly improved (P < 0.001) to the end of the study (the median of final GAS T-scores: 50, range: 25.5-63.6).
Conclusions: The applicability of GAS in CD patients was confirmed, but further large-scale studies are needed refining this innovative approach.
期刊介绍:
Movement Disorders Clinical Practice- is an online-only journal committed to publishing high quality peer reviewed articles related to clinical aspects of movement disorders which broadly include phenomenology (interesting case/case series/rarities), investigative (for e.g- genetics, imaging), translational (phenotype-genotype or other) and treatment aspects (clinical guidelines, diagnostic and treatment algorithms)