静脉溶栓治疗癌症治疗相关心功能障碍继发的小儿缺血性中风：病例报告。

IF 1 4区医学 Q3 MEDICINE, GENERAL & INTERNAL

Internal Medicine Pub Date : 2025-01-15 Epub Date: 2024-05-30 DOI:10.2169/internalmedicine.3755-24

Futoshi Eto, Tomohisa Nezu, Hideaki Sakahara, Yumiko Yamamoto, Shiro Aoki, Maiko Shimomura, Shuhei Karakawa, Hirofumi Maruyama

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引用次数: 0

摘要

一名 11 岁男孩患上了心肌栓塞性中风（CES）和癌症治疗相关心功能不全（CTRCD）。他最初患的是尤文肉瘤，接受了包括多柔比星在内的大剂量化疗。入院时，他出现严重失语，磁共振成像显示左侧大脑中动脉M3段闭塞。经胸超声心动图显示左心室严重功能障碍，左心室心尖有移动血栓。患者接受了静脉溶栓治疗，并获得了有效的再通。患者出院时未出现任何神经功能障碍。针对儿科患者的再灌注疗法尚未确立，但对继发于 CTRCD 的 CES 可能有效。

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Intravenous Thrombolysis for Pediatric Ischemic Stroke Secondary to Cancer Therapy-related Cardiac Dysfunction.

An 11-year-old boy developed cardioembolic stroke (CES) and cancer therapy-related cardiac dysfunction (CTRCD). He originally developed Ewing sarcoma and was treated with high-dose chemotherapy including doxorubicin. On admission, he had severe aphasia, and magnetic resonance imaging showed occlusion of the left middle cerebral artery M3 segment. Transthoracic echocardiography revealed severe left ventricular dysfunction and a mobile thrombus at the left ventricular apex. Intravenous thrombolysis was administered, and effective recanalization was achieved. The patient did not exhibit any neurological deficits during discharge. Reperfusion therapy for pediatric patients has not yet been established; however, it may be effective for CES secondary to CTRCD.

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来源期刊

Internal Medicine 医学-医学：内科

CiteScore

1.90

自引率

8.30%

发文量

审稿时长

2.2 months

期刊介绍： Internal Medicine is an open-access online only journal published monthly by the Japanese Society of Internal Medicine. Articles must be prepared in accordance with "The Uniform Requirements for Manuscripts Submitted to Biomedical Journals (see Annals of Internal Medicine 108: 258-265, 1988), must be contributed solely to the Internal Medicine, and become the property of the Japanese Society of Internal Medicine. Statements contained therein are the responsibility of the author(s). The Society reserves copyright and renewal on all published material and such material may not be reproduced in any form without the written permission of the Society.