杜鹃花irroratum亚种中一种新的苯乙酮衍生物

IF 1.3 4区生物学 Q4 CHEMISTRY, MEDICINAL

Phytochemistry Letters Pub Date : 2024-05-29 DOI:10.1016/j.phytol.2024.05.005

Yong-Fu Lu, Si-Xuan Liu, Chun-Lin Guo, Si-Yang Dai, Yi-Hui Yang, Chang Li, Yue-Hu Pei

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引用次数: 0

摘要

从 Rhododendron irroratum subsp. pogonostylum 中分离出了一种以前未曾描述过的苯乙酮衍生物，命名为 rhodoirroratin (1)，同时还从该属植物中首次分离出了四种已知化合物 (2-5)。在大量光谱分析的基础上阐明了它们的结构，并通过核磁共振计算分析确定了化合物 1 的绝对构型。化合物 1-3 对 LPS 诱导的 RAW264.7 细胞 NO 释放有影响。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

A new acetophenone derivative from Rhododendron irroratum subsp. pogonostylum

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A new acetophenone derivative from Rhododendron irroratum subsp. pogonostylum

One previously undescribed acetophenone derivative, named as rhodoirroratin (1), was isolated from Rhododendron irroratum subsp. pogonostylum along with four known compounds (2–5), which were isolated from the genus for the first time. Their structures were elucidated on the basis of extensive spectroscopic analysis, and the absolute configuration of compound 1 was assigned by the calculated NMR analysis. Compounds 1–3 had effects on LPS-induced NO release in RAW264.7 cells.

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来源期刊

Phytochemistry Letters 生物-生化与分子生物学

CiteScore

3.00

自引率

11.80%

发文量

190

审稿时长

34 days

期刊介绍： Phytochemistry Letters invites rapid communications on all aspects of natural product research including: • Structural elucidation of natural products • Analytical evaluation of herbal medicines • Clinical efficacy, safety and pharmacovigilance of herbal medicines • Natural product biosynthesis • Natural product synthesis and chemical modification • Natural product metabolism • Chemical ecology • Biotechnology • Bioassay-guided isolation • Pharmacognosy • Pharmacology of natural products • Metabolomics • Ethnobotany and traditional usage • Genetics of natural products Manuscripts that detail the isolation of just one new compound are not substantial enough to be sent out of review and are out of scope. Furthermore, where pharmacology has been performed on one new compound to increase the amount of novel data, the pharmacology must be substantial and/or related to the medicinal use of the producing organism.