[玻璃体粘膜牵引:诊断、自然病程、治疗决定和指南建议]。

Die Ophthalmologie Pub Date : 2024-06-01 Epub Date: 2024-05-29 DOI:10.1007/s00347-024-02042-4
Henrik Faatz, Lars-Olof Hattenbach, Tim U Krohne, Siegfried G Priglinger, Albrecht Lommatzsch
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引用次数: 0

摘要

玻璃体牵引是玻璃体后限界膜的牵引性眼窝粘连,导致玻璃体-眼窝界面的病理结构改变。这必须与生理性玻璃体粘连区分开来,生理性玻璃体粘连表现为完全保留的眼窝凹陷。症状取决于黄斑病变的严重程度,通常包括视力下降、阅读困难和变形。高分辨率光谱域光学相干断层扫描(SDOCT)成像可对有时仅为细微的形态变化进行分类。如果明显的玻璃体牵引伴有视网膜外胶质细胞增生和视网膜外层的改变,则被称为玻璃体牵引综合征。玻璃体牵引很有可能在 12 个月内自发缓解。因此,只有在患者遭受过度痛苦、双侧视力出现症状且无法自发缓解的情况下,才应进行治疗。对于伴有黄斑孔的玻璃体粘膜牵引,除了进行玻璃体旁切除术外,还讨论了其他治疗方案,如玻璃体内注射奥曲肽和气动玻璃体溶解术。在比较研究中,玻璃体切除术的解剖效果最好。由于视网膜撕裂的风险增加,对气动玻璃体溶解术的讨论存在争议。德国眼科协会目前的一份 S1 指南总结了诊断和治疗玻璃体粘膜牵引的循证建议。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Vitreomacular traction: diagnostics, natural course, treatment decision and guideline recommendations].

Vitreomacular traction is a tractive foveolar adhesion of the posterior vitreous limiting membrane, resulting in pathological structural alterations of the vitreomacular interface. This must be differentiated from physiological vitreomacular adhesion, which exhibits a completely preserved foveolar depression. Symptoms depend on the severity of the macular changes and typically include reduced visual acuity, reading problems and metamorphopsia. High-resolution spectral domain optical coherence tomography (SDOCT) imaging enables classification of the sometimes only subtle morphological changes. If pronounced vitreomacular traction is accompanied by epiretinal gliosis and alterations to the outer retina, it is referred to as a vitreomacular traction syndrome. Vitreomacular traction has a high probability of spontaneous resolution within 12 months. Therefore, treatment should only be carried out in cases of undue suffering of the patient and with symptoms during bilateral vision and a lack of spontaneous resolution. In addition to pars plana vitrectomy, alternative treatment options, such as intravitreal injection of ocriplasmin and pneumatic vitreolysis are discussed for vitreomacular traction with an associated macular hole; however, ocriplasmin is no longer available in Germany. The best anatomical results in comparative investigations were achieved by vitrectomy. Pneumatic vitreolysis is controversially discussed due to the increased risk of retinal tears. In one of the current S1 guidelines of the German ophthalmological societies evidence-based recommendations for the diagnostics and treatment of vitreomacular traction are summarized.

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