Nilam Santosh Lohakare, Dr Vaibhav Gulabrao Bhamare, Nikhil Dadaji Chavan, Shruti Dnyaneshwar Shelar, Harshal Dattatray Mahajan, Dr Rakesh Devidas Amrutkar
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Ethosome: An Innovative Perspective of Drug Delivery.
Ethosome offers a unique solution to the challenges faced by conventional drug delivery systems. In comparison to traditional liposomes and other nanocarriers, ethosomes exhibit a unique ability to improve drug absorption, overcoming a major limitation in the Transdermal Drug Delivery System. Their soft and flexible nano-vesicular structure facilitates faster permeation, resulting in significantly higher transdermal flux. This scientific investigation effectively traverses the changing landscape of ethosomes as an innovative drug delivery system. By conducting a thorough comparative analysis, we uncover the distinct characteristics that set them apart from other nanocarriers, offering insights into their distinct advantages. The study also includes a detailed analysis of the variables that have a complex impact on performance, elucidating transport mechanisms and addressing advanced facets pivotal for refined drug delivery strategies. This comprehensive overview highlights ethosomes as a future of medicine, offering a promising future for the safe and effective treatment of diverse diseases, impacting numerous lives.
期刊介绍：
Pharmaceutical Nanotechnology publishes original manuscripts, full-length/mini reviews, thematic issues, rapid technical notes and commentaries that provide insights into the synthesis, characterisation and pharmaceutical (or diagnostic) application of materials at the nanoscale. The nanoscale is defined as a size range of below 1 µm. Scientific findings related to micro and macro systems with functionality residing within features defined at the nanoscale are also within the scope of the journal. Manuscripts detailing the synthesis, exhaustive characterisation, biological evaluation, clinical testing and/ or toxicological assessment of nanomaterials are of particular interest to the journal’s readership. Articles should be self contained, centred around a well founded hypothesis and should aim to showcase the pharmaceutical/ diagnostic implications of the nanotechnology approach. Manuscripts should aim, wherever possible, to demonstrate the in vivo impact of any nanotechnological intervention. As reducing a material to the nanoscale is capable of fundamentally altering the material’s properties, the journal’s readership is particularly interested in new characterisation techniques and the advanced properties that originate from this size reduction. Both bottom up and top down approaches to the realisation of nanomaterials lie within the scope of the journal.
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