Aditi Vashisht, Arvind Krishna, Robin Chugh, Abhinav David, Divyanshu Srivastava
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A number of therapeutic approaches like surgical techniques and non-surgical techniques are performed to improve scarring.</p><p><strong>Aims and objectives: </strong>The aim of this study was to compare the outcome of subcision followed by microneedling versus subcision followed by microneedling and topical platelet-rich plasma (PRP) in atrophic scars.</p><p><strong>Materials and methods: </strong>A comparative prospective study was conducted at a tertiary care hospital in North India to compare the efficacy of subcision followed by microneedling versus subcision followed by microneedling and topical PRP. A total of 40 cases were taken and were randomly divided into two groups, A and B of 20 patients in each group. Topical PRP was applied as an additional therapy in Group B in the same sitting. Minimum three sittings were done in each patient at an interval of 4 weeks and results were assessed after 1 month of the third session. 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引用次数: 0
摘要
背景：疤痕是伤口修复的一个生物学过程，它导致皮肤的正常结构和功能发生变化，表现为凹陷或隆起的区域。疤痕的治疗具有挑战性。许多治疗方法，如手术技术和非手术技术，都是为了改善疤痕：本研究的目的是比较在萎缩性疤痕中采用亚切口后进行微针治疗与采用亚切口后进行微针治疗和局部富血小板血浆（PRP）治疗的效果：在印度北部的一家三甲医院进行了一项前瞻性对比研究，以比较亚切口后进行微针治疗与亚切口后进行微针治疗和局部富血小板血浆治疗的疗效。该研究共选取了 40 个病例，随机分为 A、B 两组，每组 20 名患者。B 组在同一疗程中使用局部 PRP 作为附加疗法。每名患者至少接受三次治疗，每次间隔 4 周，第三次治疗 1 个月后评估结果。使用 Microsoft Excel 和 SPSS 软件程序 24.0 版进行数据分析，并使用 Microsoft Word 生成图表：结果：与 A 组相比，B 组疤痕等级的改善幅度更大，差异有统计学意义（P = 0.032）。A组和B组分别有15%和30%的患者疤痕等级从4级疤痕改善到2级，B组患者的皮肤质地和色素沉着改善程度更大：结论：事实证明，PRP 与亚切削术和微针疗法相结合，能有效改善萎缩性疤痕的等级。
PRP and its benefit as an adjunctive therapy with subcision and microneedling in atrophic scars: a comparative study.
Context: Scarring is a biological process of wound repair which leads to a difference in the normal structure and function of the skin and manifests as a depressed or raised area. Treatment of scars is challenging. A number of therapeutic approaches like surgical techniques and non-surgical techniques are performed to improve scarring.
Aims and objectives: The aim of this study was to compare the outcome of subcision followed by microneedling versus subcision followed by microneedling and topical platelet-rich plasma (PRP) in atrophic scars.
Materials and methods: A comparative prospective study was conducted at a tertiary care hospital in North India to compare the efficacy of subcision followed by microneedling versus subcision followed by microneedling and topical PRP. A total of 40 cases were taken and were randomly divided into two groups, A and B of 20 patients in each group. Topical PRP was applied as an additional therapy in Group B in the same sitting. Minimum three sittings were done in each patient at an interval of 4 weeks and results were assessed after 1 month of the third session. The statistical software used is Microsoft Excel and SPSS software program, version 24.0 for analysis of data and Microsoft Word to generate graphs and tables.
Results: Improvement in scar grading was more in Group B as compared to Group A with statistically significant difference (P = 0.032). There was an improvement in scar grading from grade 4 scar to grade 2 in 15% and 30% patients of Groups A and B, respectively, with improvement in skin texture and pigmentation more in Group B.
Conclusion: PRP proved to add to the improvement of grade of atrophic scars when combined with subcision and microneedling.
期刊介绍：
The journal will cover aspects of Dermatosurgery and Aesthetic surgery, including cutaneous surgical procedures, lasers, light based treatments and aesthetic treatments. Authors of articles addressing topics such as skin tumours, pigmentary disorders, histopathology, diagnostic techniques, drugs, applications of cosmeceuticals surgical aspects, including pre and post procedural care are highly encouraged to submit with us. The journal also publishes articles on topics in allied specialities suh as plastic surgery, maxillofacial surgery vascular surgery, oculoplastic surgery etc. that are relevant to Dermatosurgery. The journal gives preference to clinically oriented studies over experimental and animal studies. The Journal would publish peer-reviewed Original Research Articles, Systematic reviews, Narrative Reviews, Case reports, Innovations and Debates. Letters to the editor, practice points, pearls in cutaneous and aesthetic surgery, quiz page, images, novel techniques, newer uses of instruments and video presentations and ethical aspects of cutaneous and aesthetic surgery are also invited.
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