生物制剂方法--何时、为何、如何？

IF 0.4 4区医学 Q4 SPORT SCIENCES

Operative Techniques in Sports Medicine Pub Date : 2024-06-01 DOI:10.1016/j.otsm.2024.151082

Daniel J. Stokes , Nicholas A. Felan , Kade S. McQuivey , Beau M. McGinley , Rachel M. Frank

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引用次数: 0

摘要

目前正在研究矫形生物制剂，以治疗各种运动医学病症。本文以证据为基础，总结了目前可用的方案，包括粘液补充剂、富血小板血浆、骨髓抽吸物浓缩、脂肪间充质干细胞和羊膜间充质干细胞。在临床实践中使用正生物技术必须了解适应症、支持证据、风险和益处。在遵守监管准则的同时，还应保持安全、成本效益高和资源意识强的方法。本文为了解何时、为何以及如何使用矫形生物学奠定了基础。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Biologics Approaches—When, Why, and How?

Orthobiologics are being investigated to treat a variety of sports medicine pathologies. This article provides an evidence-based approach summarizing currently available options, including viscosupplementation, platelet-rich plasma, bone marrow aspirate concentration, adipose-derived mesenchymal stem cells, and amniotic-derived mesenchymal stem cells. Orthobiologic use in clinical practice necessitates an understanding of the indications, supporting evidence, risks, and benefits. It should maintain a safe, cost-effective, and resource-conscious approach while adhering to regulatory guidelines. This article provides a foundation for understanding when, why, and how to implement orthobiologics.

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来源期刊

Operative Techniques in Sports Medicine 医学-外科

CiteScore

0.60

自引率

0.00%

发文量

审稿时长

93 days

期刊介绍： Operative Techniques in Sports Medicine combines the authority of a textbook, the usefulness of a color atlas and the timeliness of a journal. Each issue focuses on a single clinical condition, offering several different management approaches. It''s the easiest way for practitioners to stay informed of the latest surgical advancements and developments.