从肠道到胆红素 揭开肠道功能衰竭相关肝病的机理:叙述性综述

Yugam Rajeshkumar Oza, H. M. Joshi, Sameeha Fatima Khan, Amna Shahid Bilal, Ali Zeeshan Murtuza, Vidhi Mashru
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引用次数: 0

摘要

与肝脏疾病相关的肠功能衰竭(IFALD)是一种复杂的疾病,在儿科人群中的发病率为 40-60%,在成人中的发病率为 15-40%[1]。与肝脏相关的疾病包括胆汁淤积症、胆囊疾病、脂肪性肝炎和胆汁性肝硬化[1]。由于 IFALD 的病因复杂,导致它的因素很多,但肠外给药(PN)仍然是关键原因。不同年龄段的患者表现出的症状和体征各不相同,因此治疗策略也相应不同。这篇综述包括导致 IFALD 的危险因素和错综复杂的发病机制,我们可以通过改变饮食来预防 IFALD 的发生,最后最重要的是管理技术和治疗方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
FROM BOWELS TO BILIRUBIN UNRAVELING THE MECHANISM OF INTESTINAL FAILURE ASSOCIATED LIVER DISEASE: A NARRATIVE REVIEW
Intestinal failure associated with liver disease (IFALD) is an intricate illness having the prevalence of 40-60% in paediatric population and 15-40% in adults [1]. The diseases corresponding with liver include cholestasis, gall bladder disease, steatohepatitis, and biliary cirrhosis [1]. Since IFALD has a complicated etiology there are many factors causing it but parenteral administration (PN) remains the key reason. Each patient of a different age group presents with varying symptoms and signs, so the treatment strategy is tailored accordingly. This review encompasses the risk factors causing IFALD along with the intricate pathogenesis, the changes that can be bought in our diet to prevent it from occurring and last most importantly the management techniques along with the line of treatment.
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