干眼症与血脂异常的关系研究

Sonali Agrawal, Nupur Suman
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引用次数: 0

摘要

目的:本研究调查了干眼症(DED)与血脂异常的关系。研究还评估了血脂异常患者视觉显示终端(VDT)与 DED 的关联。此外,还研究了血脂异常患者 DED 中的睑板腺功能障碍(MGD)。研究对象为 60 名 20-60 岁的血脂异常患者。在获得知情同意、询问病史和使用问卷进行直接访谈后,在进行 DEEP 评分前,重点了解干眼病史。评估包括 VDT 使用、视力、裂隙灯检查眼部过敏体征和睑板腺功能障碍程度。诊断性测试(泪液破裂时间(tBUT)、荧光素染色、施尔默试验)确定干眼症分级。根据性别和干眼状态对患者进行分类。分析血清脂质水平以确定血脂异常与干眼症的关系。血脂异常的标准包括胆固醇、甘油三酯、低密度脂蛋白 (LDL) 和高密度脂蛋白 (HDL) 水平升高。在女性中,DED 与血脂异常之间存在显著的cant association 结果与发现:DED 与血脂异常之间存在显著的相关性(p < 0.001),其中总胆固醇显示出明显的相关性,尤其是在女性中。女性血脂异常与 DED 之间的相关性比男性更为突出。此外,DED 和非 DED 患者的 MGD 也存在明显差异(p = 0.001)。研究结果表明,女性 DED 进展与血脂异常之间存在密切联系。对患者进行干眼症教育和眼科医生对血脂异常的诊断可以预防失明和心血管疾病。t-BUT 在 VDT 使用者中受到显著影响,这表明使用 VDT 会使泪液lm 变得不稳定,因此有助于,确定干眼症与使用 VDT 的实际相关性。MGD在统计学上有显著cance (p = 0.001),导致泪液lm改变、眼刺激、内ammation和眼表疾病。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A STUDY ON THE ASSOCIATION OF DRY EYE WITH DYSLIPIDEMIA
Aim: This study investigates the association of dry eye disease (DED) with dyslipidemia. The study also assessed the association of visual display terminal (VDT) and DED in patients with dyslipidemia. The meibomian gland dysfunction (MGD) in DED in patients with dyslipidemia was also studied. In the OPD, 60 patients aged 20-60 years with dyslipidemia were studied. After obtaining i Methods: nformed consent, medical history, and direct interviews using a questionnaire, emphasis was placed on dry eye history before applying the DEEP score. Assessments included VDT use, visual acuity, slit lamp examination for ocular allergy signs, and meibomian gland dysfunction degree. Diagnostic tests (Tear break up time (tBUT), Fluorescein staining, Schirmer's test) determined dry eye grading. Patients were categorized by gender and dry eye status. Serum lipid levels were analyzed to establish the dyslipidemia-DED association. Dyslipidemia criteria included elevated cholesterol, triglycerides, low-density lipoprotein (LDL), and low high-density lipoprotein (HDL) levels. In women, a signicant associatio Results And Findings: n exists between DED and dyslipidemia (p < 0.001), with total cholesterol showing notable relevance, particularly in women. The correlation between dyslipidemia and DED is more prominent among women than men. There was a major difference between the VDT usage in patients with and without DED. Additionally, a substantial difference in MGD is evident between DED and non-DED patients (p = 0.001). Findings reveal a robust Conclusion: association between DED progression and dyslipidemia in women. Patient education on dry eye and ophthalmologists diagnosing dyslipidemia can prevent blindness and cardiovascular disease. t-BUT is affected signicantly among VDT users shows that tear lm becomes unstable by their usage, hence helps in nding the actual correlation of dry eye with the use of VDT. MGD demonstrates statistical signicance (p = 0.001), leading to tear lm alterations, eye irritation, inammation, and ocular surface disease.
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