肾脏中的维生素 D:一把双刃剑?

I. Burlaka, I. Mityuryayeva
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引用次数: 0

摘要

维生素 D 是人体最重要的成分之一,对健康和疾病都至关重要。它是脂溶性类固醇家族中的一员,可从饮食或阳光直接照射中获得,它将 7-羟基胆固醇转化为维生素 D 的前体。生物活化是一个交替阶段,它提供了一种活性维生素 D,有助于解毒、生育、葡萄糖调节、骨骼重塑和钙调节等多个显著过程。许多研究调查探讨了维生素 D 在肾脏疾病中的明显功能。本研究探讨了维生素 D 在糖尿病患者和非糖尿病患者肾脏中的基本生理和病理作用。本研究分析了维生素 D 在糖尿病和非糖尿病蛋白尿肾脏疾病中的基本生理和病理作用。该领域的进一步研究具有重要意义。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Vitamin D in kidney: a two-edged sword?
A wide variety of both calcium-dependent and calcium-non-dependent actions are attributed to the vitamin and hormone vitamin D. One of the most vital components of the human body, vitamin D is essential to both health and illness. It is a member of the fat-soluble secosteroid family, which is obtained from diets or direct sun exposure, which is what turns 7-hydroxycholesterol into the precursor of vitamin D. Bio-activation is an alternate phase that provides an active version of vitamin D that contributes to several notable processes like detoxification, fertility, glucose regulation, bone remodelling, and calcium regulation. Numerous research investigations examine the discernible function of vitamin D in kidney illness. The basic physiological and pathological roles of vitamin D in the kidneys of both diabetics and non-diabetics were examined in this study. In this study we analyzed a basic physiological and pathological roles of Vitamin D in kidney in terms of diabetic and non-diabetic proteinuric kidney diseases. Further research in this field is of high importance.
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