探索生物活性化合物纳米封装的不同策略及其后续方法

IF 3.4 Q2 PHARMACOLOGY & PHARMACY
Sailee Chowdhury, Koyel Kar, Rana Mazumder
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引用次数: 0

摘要

背景纳米技术在食品科学等许多领域迅速普及。可溶性生物活性物质被包裹在一个保护罩中,使其免受有害环境因素的影响。它还可以定向输送到特定区域。食品中的生物活性化合物会缓慢降解,或因氧化等外部或内部因素而发生变化。创新技术和新型可食用包装材料可用于降低生物利用率。纳米结构系统能增强多种特性,包括抗降解性和改善溶解度、稳定性和生物利用度等理化功能,因为纳米尺寸增加了表面积,从而提高了活性。本文简要讨论了最近出现的纳米封装技术,包括电喷雾、纳米流体、复合共凝胶、电纺丝、聚合等。不同的生物活性分子可以通过吸收、结合、化学作用或分散到纳米载体中来实现纳米封装。此外,还研究了其他表征技术和不同的物理化学参数,以评估封装生物活性物质的特性。本文重点介绍了利用前沿方法进行纳米封装的多种生物活性物质。纳米技术的出现为创新药物的开发、设计和配制提供了广泛的可能性。食品和制药行业可将注意力集中在通过纳米封装技术提供的各种改进而获得附加值的产品上。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Exploration of different strategies of nanoencapsulation of bioactive compounds and their ensuing approaches

Background

Nanotechnology has gained rapid popularity in many fields, such as food science. The labile bioactive is enclosed in a shield that protects it from harmful environmental factors. It also allows for targeted delivery to specific areas. Bioactive compounds in foods are slowly degraded or can change due to external or internal factors such as oxidation. Innovative technologies and novel edible packaging materials can be used to reduce bioavailability. One promising technology for overcoming the problems above is encapsulation.

The main body of the abstract

Nanostructure systems enhances a number of properties, including resistance to degradation and improvements of physicochemical functions like solubility, stability, and bioavailability, among others as the nanosize increases surface area and, consequently, activity. A recently emerged nanoencapsulation technologies, including electro spraying, nano-fluidics, complex coacervation, electrospinning, polymerization, etc. have been briefly discussed. Different bioactive molecules can be nano encapsulated by absorbing, incorporating, chemically interacting, or dispersing substances into nanocarriers. There have also been other characterization techniques and different physico chemical parameters investigated to evaluate the characteristics of encapsulated bioactives. The current article highlights numerous bioactive substances utilized for nanoencapsulation using cutting-edge methods.

Short conclusion

This review examines how different encapsulating bioactive materials can improve encapsulating films or coatings. The advent of nanotechnology has opened up a wide range of possibilities for the development, design, and formulation of innovative pharmaceuticals. The food and pharmaceutical industry can focus its attention on products that have added value through the various enhancements offered by nanoencapsulation.

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来源期刊
自引率
0.00%
发文量
44
审稿时长
23 weeks
期刊介绍: Future Journal of Pharmaceutical Sciences (FJPS) is the official journal of the Future University in Egypt. It is a peer-reviewed, open access journal which publishes original research articles, review articles and case studies on all aspects of pharmaceutical sciences and technologies, pharmacy practice and related clinical aspects, and pharmacy education. The journal publishes articles covering developments in drug absorption and metabolism, pharmacokinetics and dynamics, drug delivery systems, drug targeting and nano-technology. It also covers development of new systems, methods and techniques in pharmacy education and practice. The scope of the journal also extends to cover advancements in toxicology, cell and molecular biology, biomedical research, clinical and pharmaceutical microbiology, pharmaceutical biotechnology, medicinal chemistry, phytochemistry and nutraceuticals.
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