比克瑞持续冲洗联合负压封闭引流和富血小板血浆技术治疗 III-IV 期压迫性溃疡的临床评估。

IF 1.4 4区 医学 Q3 ALLERGY
Postepy Dermatologii I Alergologii Pub Date : 2024-04-01 Epub Date: 2024-04-09 DOI:10.5114/ada.2024.138675
Yuxin Liu, Na Chen
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引用次数: 0

摘要

导言:目的:探讨比克瑞消毒剂+真空密封引流(VSD)+富血小板血浆(PRP)治疗对Ⅲ~Ⅳ期压疮患者的效果:本研究选取我院收治的压疮(PU)患者110例,采用盲选法随机分为实验组(Exp组)和对照组(Ctrl组),每组55例。Ctrl组患者接受手术清创+VSD治疗,Exp组患者接受比克瑞消毒剂+VSD+PRP治疗。比较不同组患者的炎症反应(IR)评分、PU愈合(PUH)评分、愈合时间、换药次数(DCF)、换药间隔时间(DIT)和瘢痕恢复(SR)评分:结果显示,治疗 1 或 2 周后,Exp 组伤口分泌物细菌培养阳性率大大低于 Ctrl 组(P < 0.05)。治疗后第 1 周和第 2 周,Exp 组的 IR 评分大大低于 Ctrl 组(P < 0.05)。Exp组的总有效率(TER)明显高于Ctrl组(94.55% vs. 76.36%):结果表明,必克瑞消毒剂+VSD+PRP疗法能有效改善PU患者的炎症程度,促进患者伤口修复和瘢痕恢复,大大提高PU患者的临床疗效。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Clinical evaluation of continuous irrigation with Bikerui combined with negative pressure closed drainage and platelet-rich plasma technique for treatment of stage III-IV pressure ulcer.

Introduction: As a catastrophic complication of bedridden and elderly patients, pressure ulcer usually continuously affects patients' health and quality of life, so the daily care of wounds is attached great importance in clinic.

Aim: This work investigated the effect of Bikerui disinfectant + vacuum sealing drainage (VSD) + platelet-rich plasma (PRP) therapy on patients with stage III ~ IV pressure sore.

Material and methods: In this work, 110 patients with pressure ulcer (PU) treated in our hospital were enrolled and were randomly divided into an experimental group (Exp group) and a control group (Ctrl group) by a blind selection method, with 55 cases in each group. Patients in the Ctrl group received surgical debridement + VSD for treatment, while those in the Exp group were treated with Bikerui disinfectant + VSD + PRP. Inflammatory response (IR) score, PU healing (PUH) score, healing time, dressing change frequency (DCF), dressing interval time (DIT), and scar recovery (SR) score of patients in different groups were compared.

Results: The results revealed that the positive rate of bacterial culture in wound secretions in the Exp group was greatly lower than that in the Ctrl group 1 or 2 weeks after treatment (p < 0.05). The IR score in the Exp group was much lower at week 1 and 2 after treatment (p < 0.05). The total effective rate (TER) in the Exp group was obviously higher than that in the Ctrl group (94.55% vs. 76.36%).

Conclusions: The results suggested that Bikerui disinfectant + VSD + PRP therapy could effectively improve the inflammatory degree of PU patients, promote the wound repair and scar recovery of patients, and greatly improve the clinical efficacy of PU patients.

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来源期刊
CiteScore
2.60
自引率
7.10%
发文量
107
审稿时长
6-12 weeks
期刊介绍: Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii is a bimonthly aimed at allergologists and dermatologists.
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