德国前列腺增生症住院患者的趋势和治疗结果:GRAND 研究的结果。

IF 2.8 3区 医学 Q2 UROLOGY & NEPHROLOGY
Nikolaos Pyrgidis, Gerald B Schulz, Michael Chaloupka, Yannic Volz, Paulo L Pfitzinger, Elena Berg, Philipp Weinhold, Friedrich Jokisch, Christian G Stief, Armin J Becker, Julian Marcon
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引用次数: 0

摘要

我们的目标是通过该领域最大规模的研究,为低流量和高流量尿崩症患者的趋势和住院预后提供证据。我们使用了联邦统计局研究数据中心提供的 GeRmAn 全国住院患者数据(GRAND)(2008-2021 年),并进行了多项患者层面的分析。我们共纳入了6588名低流量男性尿崩症患者和729名高流量男性尿崩症患者。在低流量尿崩症患者中,156 人(2.4%)患有镰状细胞病,1477 人(22.4%)需要进行分流手术。其中,只有 37 人(2.5%)同时接受了阴茎假体植入手术(30 个充气假体和 7 个半硬性假体)。在德国,需要住院治疗的低流量性前列腺炎患者总人数在稳步上升,而需要住院治疗的高流量性前列腺炎患者人数在过去几年有所下降。在高流量性前列腺炎患者中,有 136 人(18.7%)需要进行选择性动脉栓塞治疗。在低流量性前列腺增生症男性患者中,镰状细胞病与高交换输血率(OR:21,95% CI:14-31,P 0.9)、输血率(P = 0.8)和重症监护室入院率(P = 0.5)相关。低流量尿崩症是绝对的急症,超过五分之一的患者需要住院进行分流手术。相反,在大多数情况下,高流量尿崩症仍可采取保守治疗。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Trends and outcomes of hospitalized patients with priapism in Germany: results from the GRAND study.

Trends and outcomes of hospitalized patients with priapism in Germany: results from the GRAND study.

We aimed to provide evidence on the trends and in-hospital outcomes of patients with low- and high-flow priapism through the largest study in the field. We used the GeRmAn Nationwide inpatient Data (GRAND), provided by the Research Data Center of the Federal Bureau of Statistics (2008-2021), and performed multiple patient-level analyses. We included 6,588 men with low-flow and 729 with high-flow priapism. Among patients with low-flow priapism, 156 (2.4%) suffered from sickle cell disease, and 1,477 (22.4%) patients required shunt surgery. Of them, only 37 (2.5%) received a concomitant penile prosthesis implantation (30 inflatable and 7 semi-rigid prosthesis). In Germany, the total number of patients with low-flow priapism requiring hospital stay has steadily increased, while the number of patients with high-flow priapism requiring hospital stay has decreased in the last years. Among patients with high-flow priapism, 136 (18.7%) required selective artery embolization. In men with low-flow priapism, sickle cell disease was associated with high rates of exchange transfusion (OR: 21, 95% CI: 14-31, p < 0.001). The length of hospital stay (p = 0.06) and the intensive care unit admissions (p = 0.9) did not differ between patients with low-flow priapism due to sickle cell disease versus other causes of low-flow priapism. Accordingly, in men with high-flow priapism, embolization was not associated with worse outcomes in terms of length of hospital stay (p > 0.9), transfusion (p = 0.8), and intensive care unit admission (p = 0.5). Low-flow priapism is an absolute emergency that requires shunt surgery in more than one-fifth of all patients requiring hospital stay. On the contrary, high-flow priapism is still managed, in most cases, conservatively.

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来源期刊
International Journal of Impotence Research
International Journal of Impotence Research 医学-泌尿学与肾脏学
CiteScore
4.90
自引率
19.20%
发文量
140
审稿时长
>12 weeks
期刊介绍: International Journal of Impotence Research: The Journal of Sexual Medicine addresses sexual medicine for both genders as an interdisciplinary field. This includes basic science researchers, urologists, endocrinologists, cardiologists, family practitioners, gynecologists, internists, neurologists, psychiatrists, psychologists, radiologists and other health care clinicians.
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