涨潮:全球儿童和青少年 2 型糖尿病患者激增,需要立即采取行动。

IF 4.2 3区 医学 Q1 ENDOCRINOLOGY & METABOLISM
Joseph M Pappachan, Cornelius James Fernandez, Ambika P Ashraf
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引用次数: 0

摘要

儿童期肥胖症已成为全球公共医疗保健领域的一大挑战,肥胖环境助长了肥胖症,遗传和表观遗传易感性也对肥胖症产生了影响。这导致儿童和青少年 2 型糖尿病的发病率呈指数级上升。成年早期与糖尿病相关的并发症浪潮迫在眉睫,预计将使大多数国家的医疗预算捉襟见肘。除非全球共同努力遏制这种情况造成的破坏,否则其影响将是巨大的。要实现这一目标,多方面的研究工作、政府立法和有效的社会行动至关重要。本文深入研究了当前的流行病学状况,探讨了有关潜在风险和后果的证据,深入研究了儿童肥胖症的病理生物学,并讨论了基于证据的最新肥胖症管理策略。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Rising tide: The global surge of type 2 diabetes in children and adolescents demands action now.

Childhood-onset obesity has emerged as a major public healthcare challenge across the globe, fueled by an obesogenic environment and influenced by both genetic and epigenetic predispositions. This has led to an exponential rise in the incidence of type 2 diabetes mellitus in children and adolescents. The looming wave of diabetes-related complications in early adulthood is anticipated to strain the healthcare budgets in most countries. Unless there is a collective global effort to curb the devastation caused by the situation, the impact is poised to be pro-found. A multifaceted research effort, governmental legislation, and effective social action are crucial in attaining this goal. This article delves into the current epidemiological landscape, explores evidence concerning potential risks and consequences, delves into the pathobiology of childhood obesity, and discusses the latest evidence-based management strategies for diabesity.

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来源期刊
World Journal of Diabetes
World Journal of Diabetes ENDOCRINOLOGY & METABOLISM-
自引率
2.40%
发文量
909
期刊介绍: The WJD is a high-quality, peer reviewed, open-access journal. The primary task of WJD is to rapidly publish high-quality original articles, reviews, editorials, and case reports in the field of diabetes. In order to promote productive academic communication, the peer review process for the WJD is transparent; to this end, all published manuscripts are accompanied by the anonymized reviewers’ comments as well as the authors’ responses. The primary aims of the WJD are to improve diagnostic, therapeutic and preventive modalities and the skills of clinicians and to guide clinical practice in diabetes. Scope: Diabetes Complications, Experimental Diabetes Mellitus, Type 1 Diabetes Mellitus, Type 2 Diabetes Mellitus, Diabetes, Gestational, Diabetic Angiopathies, Diabetic Cardiomyopathies, Diabetic Coma, Diabetic Ketoacidosis, Diabetic Nephropathies, Diabetic Neuropathies, Donohue Syndrome, Fetal Macrosomia, and Prediabetic State.
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