可视化基因组医学

Caryn Babian, Sudhir Kumar
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引用次数: 0

摘要

新兴的基因组医学领域为生物和解剖学教师提供了一个将 DNA、遗传学、分子过程和进化等主题融为一体的机会。通过基因组医学范例,学生们可以看到突变等小的生物课题与疾病表型之间的潜在联系。在本文中,我们以囊性纤维化为例,通过基因组医学的视角对囊性纤维化这一普通生物课上经常学习的遗传疾病进行研究。基因、质膜、变异、突变、细胞核和染色体等概念可以通过基因组医学的视角,以叙述和直观的方式来介绍遗传学,让学生参与到下一代基因组学和生命的基本单位--细胞中,并与之建立联系。正是通过基因组医学的视角,细胞的背景和与不断发展的世界的关系才得以展现。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Visualizing Genomic Medicine
The emerging field of genomic medicine offers an opportunity for biology and anatomy teachers to bring the topics of DNA, genetics, molecular processes, and evolution together into one experience. Through the genomic medicine paradigm, students see the unbroken connection between small biological topics such as mutations and their potential connection to disease phenotypes. In this paper, we present as a main example cystic fibrosis, which is an often-studied genetic disease in general biology class, for examination through the genomic medicine lens. Concepts such as genes, the plasma membrane, variation, mutations, the nucleus, and chromosomes can be used in a narrative and visual approach to genetics through the genomic medicine standpoint to engage and connect students with next-generation genomics and with the fundamental unit of life—the cell. It is through the genomic medicine lens that the cell’s context and relationship to the evolving world takes place.
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