氢氧化钙与三氧化氢矿物骨料和再生根管治疗在顶点化过程中诱导根尖闭合方面的比较 - 系统回顾和 Meta 分析

Q3 Dentistry
Divya Gupta, A. K. Shaw, Sheetal D. Mali, Abhijit B. Jadhav
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引用次数: 0

摘要

本研究旨在评估再生根管治疗术(REP)与使用三氧化氢矿物质骨料(MTA)和氢氧化钙的根尖封闭治疗术(AP)在诱导根尖封闭方面的更好效果。研究遵循了系统综述和元分析首选报告项目(PRISMA)指南,并在 PROSPERO-CRD42023398997 中进行了注册。在电子数据库中搜索了从存活率、成功率、根长增加、根宽增加和根尖直径减少等方面评估 REP 和 AP 效果的研究。使用 RevMan 5.3 版的 Cochrane 偏倚风险(RoB)-2 工具进行质量评估。风险比(RR)和标准化平均差(SMD)被用作随机效应模型的汇总统计量(P < 0.05)。定性综合纳入了 9 项研究,荟萃分析纳入了 8 项研究。质量评估显示存在中度至低度偏倚风险。通过RR和SMD的汇总估计结果显示,REP优于AP,其存活率更高(RR = 1.01 (0.96 - 1.06)),成功率更高(RR = 1.09 (0.96 - 1.24)),根长增加(SMD = 0.25 (-0.14 - 0.63)),根宽增加(0.66 (0.22 - 1.10)),根尖直径减少(SMD =0.66 (-0.51 - 1.83))。漏斗图未显示任何异质性,表明不存在发表偏倚。REP 能明显改善根尖末端封闭。AP在形成钙化屏障方面同样有效,但得出的结论是,再生术比根尖封闭术效果更好。临床医生应该考虑在牙根发育严重不足的情况下采用 REP,即使采用牙尖修复术,牙齿的预后也没有希望。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Comparison between Calcium Hydroxide with Mineral Trioxide Aggregate and Regenerative Endodontics in Inducing Root Apex Closure during Apexification – A Systematic Review and Meta-analysis
This study aimed to assess better effectiveness between regenerative endodontic procedures (REP) and apexification procedures (AP) with mineral trioxide aggregate (MTA) and calcium hydroxide for inducing root end apex closure. Preferred Reporting Items for Systematic Reviews and Meta- Analysis (PRISMA) guidelines were followed and registered in PROSPERO-CRD42023398997. Electronic databases were searched for studies evaluating effectiveness of REP and AP in terms of survival rate, success rate, increase in root length, root width and decrease in apical diameter. Cochrane risk of bias (RoB) -2 tool was used for quality assesssment using RevMan 5.3. The risk ratio (RR) and standardized mean difference (SMD) was used as summary statistic measure with random effect model (P < 0.05). Nine studies were included in qualitative synthesis and eight studies for meta-analysis. Quality assessment revealed moderate to low risk of bias. The pooled estimate through RR and SMD favoured REP being superior to AP for better survival rate (RR = 1.01 (0.96 – 1.06)), success rate (RR = 1.09 (0.96 – 1.24)), increase in root length (SMD = 0.25 (-0.14 – 0.63)), root width (0.66 (0.22 – 1.10)) and decrease in apical diameter (SMD =0.66 (-0.51 – 1.83)). Funnel plot did not show any heterogeneity indicating absence of publication bias. REP significantly improved apical root end closure. AP are equally effective in forming calcific barrier, however it was concluded that regeneration procedures are comparably superior to apexification procedures with greater outcomes. Clinicians should consider employing the REP in cases when root development is severely deficient and where tooth's prognosis is hopeless even with an apexification procedure.
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来源期刊
Indian Journal of Dental Research
Indian Journal of Dental Research Dentistry-Dentistry (all)
CiteScore
1.80
自引率
0.00%
发文量
80
审稿时长
38 weeks
期刊介绍: Indian Journal of Dental Research (IJDR) is the official publication of the Indian Society for Dental Research (ISDR), India section of the International Association for Dental Research (IADR), published quarterly. IJDR publishes scientific papers on well designed and controlled original research involving orodental sciences. Papers may also include reports on unusual and interesting case presentations and invited review papers on significant topics.
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