脊髓许旺瘤手术后与健康相关的生活质量和重返工作岗位:一项基于人群的队列研究

Cancers Pub Date : 2024-05-15 DOI:10.3390/cancers16101882
Aman Singh, Ann-Christin von Vogelsang, V. G. El-Hajj, Ali Buwaider, Alexander Fletcher-Sandersjöö, Jenny Pettersson-Segerlind, E. Edström, Adrian Elmi-Terander
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引用次数: 0

摘要

脊柱裂孔瘤是第二大最常见的原发性脊柱硬膜内肿瘤。本研究旨在评估脊柱裂孔瘤手术治疗后与健康相关的生活质量(HRQoL)和重返工作岗位的频率。HRQoL与普通人群样本进行了比较。先前的一项研究确定了2006年至2020年期间接受脊柱裂孔瘤手术的患者,并要求随访时仍健在的患者(180人中的171人)参与研究。94名患者(56%)做出了回应,并被纳入本研究。数据与 2006 年斯德哥尔摩公共卫生调查进行了比较,后者是一项对具有代表性的普通人群样本进行的横断面调查。对任何潜在的非响应偏差进行了分析,结果显示两组之间没有显著差异。除一个维度外,脊髓分裂瘤样本与普通人群样本在所有维度上的 HRQoL 都相同;脊髓分裂瘤样本中的男性比普通人群中的男性在日常活动维度上报告了更多中度问题(p = 0.020)。在脊神经分裂瘤样本中,男性和女性在 EQ-5Dindex 或 EQVAS 两个维度上都没有显著差异。手术前,共有 71 人(76%)从事全职工作,手术后,几乎所有人(94%)都重返工作岗位,其中大部分人在手术后 3 个月内重返工作岗位。89名患者(95%)回答说,如果今天再问他们,他们会接受脊神经分裂瘤手术治疗。总之,脊管分裂瘤的手术治疗与良好的 HRQoL 和恢复工作的高频率有关。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Health-Related Quality of Life and Return to Work after Surgery for Spinal Schwannoma: A Population-Based Cohort Study
Spinal schwannomas are the second most common primary intradural spinal tumor. This study aimed to assess health-related quality of life (HRQoL) and the frequency of return to work after the surgical treatment of spinal schwannomas. HRQoL was compared to a sample of the general population. Patients operated for spinal schwannomas between 2006 and 2020 were identified in a previous study and those alive at follow-up (171 of 180) were asked to participate. Ninety-four (56%) responded and were included in this study. Data were compared to the Stockholm Public Health Survey 2006, a cross-sectional survey of a representative sample of the general population. An analysis for any potential non-response bias was performed and showed no significant differences between the groups. HRQoL was equal between the spinal schwannoma sample and the general population sample in all but one dimension; men in the spinal schwannoma sample reported more moderate problems in the usual activities dimension than men in the general population (p = 0.020). In the schwannoma sample, there were no significant differences between men and women in either of the dimensions EQ-5Dindex or EQVAS. Before surgery, a total of 71 (76%) were working full-time and after surgery almost all (94%) returned to work, most of them within 3 months of surgery. Eighty-nine (95%) of the patients responded that they would accept the surgery for their spinal schwannoma if asked again today. To conclude, surgical treatment of spinal schwannomas is associated with good HRQoL and with a high frequency of return to work.
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