从神经行为学角度看自闭症谱系障碍

Lleuvelyn A. Cacha
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引用次数: 0

摘要

近几十年来,人们对自闭症的遗传和环境影响有了更深入的了解。然而,它们交织在一起导致自闭症的机制仍有待进一步探索。DSM-5 中的自闭症诊断是由神经发育障碍导致的,这种障碍会损害大脑的正常功能,影响沟通和社会交往,并伴有行为和兴趣的局限性或重复性。本文回顾了目前研究大脑结构和功能的潜在机制与自闭症复杂异常的行为表现之间关系的工作。绘制这种联系的图谱可以让我们更好地理解自闭症的体征和症状,从而使准确诊断的过程更加简单明了。作为一种复杂的神经行为疾病,自闭症患者与非自闭症患者处理环境和与他人互动的方式不同。因此,他们对自身与环境的感知和联系也不同。因此,他们在沟通、建立关系和对环境做出适当反应时会遇到困难。正是这种终生的神经行为功能障碍使自闭症患者无法充分理解自己的感知和他人的情感表达。他们的精神状态、大脑工作方式和思维过程都会因神经发育障碍而受到影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Neurobehavioral perspectives on autistic spectrum disorder
Understanding genetics and environmental influences in autism has been explored in greater depth in recent decades. However, the mechanism by which they converge that leads to autism still needs to be explored further. An autism diagnosis in DSM-5 results from a neurodevelopmental disorder hurting normal brain function, affecting communication and social interaction combined with restricted or repetitive patterns of behavior and interests. This paper reviews current work investigating how the underlying mechanism of the brain structure and function relates to the complex and aberrant behavioral manifestations of autism. Mapping this connection can provide us with a better understanding of autism signs and symptoms, making the process of accurate diagnosis more straightforward. As a complex neurobehavioral condition, autistic individuals process the environment and their interactions with others differently from those without autism. So, they make different perceptions and connections between themselves and the environment. Consequently, they will have difficulty communicating, forming relationships, and responding appropriately to their environment. It is this lifelong neurobehavioral dysfunction that prevents autistic individuals from adequately understanding what they perceive and the emotional expression of others. There will be differences in their mental states, how their brains work, and how their thinking processes will be affected by a neurodevelopmental disability.
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