探索膳食中欧米茄-3 和欧米茄-6 脂肪酸摄入量与类风湿性关节炎风险之间的联系:NHANES 1999-2020 研究。

IF 3.4 4区 医学 Q2 RHEUMATOLOGY
Tianlun Kang, Yajing Xi, Tangliang Qian, Siyi Lu, Mengmeng Du, Xiaojun Shi, Xiujuan Hou
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引用次数: 0

摘要

目的:n-3和n-6脂肪酸的摄入与类风湿性关节炎(RA)之间的关系仍不清楚。为解决这一问题,本研究利用了1999年至2020年期间美国国家健康与营养调查(NHANES)的数据:n-3和n-6脂肪酸的膳食摄入量信息是通过24小时膳食回忆访谈收集的,并根据体重进行了调整。通过问卷调查收集 RA 患者数据。采用逻辑回归和样条分析法对相关性进行评估。研究共纳入了 50,352 名横断面参与者:在调整后的模型 2 中,与最低类别相比,n-3 和 n-6 脂肪酸摄入量的几率比(ORs)分别为 0.72(95% CI:0.60-0.86)和 0.76(95% CI:0.62-0.92):结论:研究结果表明,在美国成年人中,n-3 和 n-6 脂肪酸的摄入量与类风湿性关节炎的发病风险呈负相关。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Exploring the link between dietary omega-3 and omega-6 fatty acid intake and rheumatoid arthritis risk: NHANES 1999-2020 study.

Objectives: The association between the ingestion of n-3 and n-6 fatty acids and rheumatoid arthritis (RA) remains unclear. To address this, this study utilised data from the National Health and Nutrition Examination Survey (NHANES) spanning from 1999 to 2020.

Methods: Dietary intake information on n-3 and n-6 fatty acids was gathered through 24-hour interviews about dietary recall and adjusted based on weight. RA patient data was collected using questionnaires. Associations were evaluated using logistic regression and spline analyses. The study included a total of 50,352 participants in a cross-sectional manner.

Results: In the adjusted Model 2, higher odds ratios (ORs) of 0.72 (95% CI: 0.60-0.86) and 0.76 (95% CI: 0.62-0.92) were observed for n-3 and n-6 fatty acid intake, respectively, compared to the lowest category.

Conclusions: The results suggest a negative correlation between the ingestion of n-3 and n-6 fatty acids and the risk of rheumatoid arthritis in US adults.

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来源期刊
CiteScore
6.10
自引率
18.90%
发文量
377
审稿时长
3-6 weeks
期刊介绍: Clinical and Experimental Rheumatology is a bi-monthly international peer-reviewed journal which has been covering all clinical, experimental and translational aspects of musculoskeletal, arthritic and connective tissue diseases since 1983.
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