成人分化型甲状腺癌的分子成像与治疗

IF 2.6 4区医学 Q3 ONCOLOGY

Cancer journal Pub Date : 2024-05-01 DOI:10.1097/PPO.0000000000000713

Philipose Getachew Mulugeta, Anthony W Chi, Thomas Michael Anderson

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引用次数: 0

摘要

摘要：过去几十年来，分化型甲状腺癌（DTC）在美国的发病率不断上升，但死亡率一直很低。自 20 世纪 40 年代以来，放射性碘治疗（RAI-T）一直是治疗 DTC 的主要方法。RAI-T 治疗前后 DTC 的成像主要集中在碘化钠合剂的分子成像上。随着对 DTC 分子特征认识的不断深入，可供选择的治疗方案也越来越多。将风险分层纳入治疗方法后，手术和非手术治疗的强度都有所降低，从而在不影响疾病控制的情况下降低了发病率。

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Molecular Imaging and Therapy of Differentiated Thyroid Carcinoma in Adults.

Abstract: Differentiated thyroid carcinoma (DTC) has been increasing in incidence in the United States over the last several decades, although mortality rates have remained low. Radioactive iodine therapy (RAI-T) has been a mainstay of treatment for DTC since the 1940s. Imaging of DTC before and after RAI-T primarily focuses on molecular imaging of the sodium iodide symporter. The expanding understanding of the molecular profile of DTC has increased available treatment options. Incorporation of risk stratification to treatment approaches has led to deintensification of both surgical and nonsurgical treatments, leading to decreased morbidity without compromising disease control.

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来源期刊

Cancer journal 医学-肿瘤学

CiteScore

3.90

自引率

0.00%

发文量

102

审稿时长

7.5 months

期刊介绍： The Cancer Journal: The Journal of Principles & Practice of Oncology provides an integrated view of modern oncology across all disciplines. The Journal publishes original research and reviews, and keeps readers current on content published in the book Cancer: Principles & Practice of Oncology.