小儿颞叶肿瘤相关癫痫的神经认知。

IF 1.6 4区心理学 Q3 PSYCHOLOGY

Developmental Neuropsychology Pub Date : 2024-07-01 Epub Date: 2024-05-16 DOI:10.1080/87565641.2024.2354745

Elise M Turner, Emily Olsen, Susanne Duvall

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引用次数: 0

摘要

在小儿颞叶肿瘤患者中，肿瘤相关癫痫是一种常见的神经系统合并症，但对其研究不足，它可能导致神经认知障碍（NCI）。41 名患有颞叶肿瘤+（n = 23）或非肿瘤性颞叶癫痫（n = 18）的 6-20 岁青少年完成了常规神经心理学评估。各组的 NCI 发生率相似；但是，在语音流利性任务中，非肿瘤性参与者的 NCI 发生率更高，P = .047。仅在 TLT+ 参与者中，较年轻的癫痫发作年龄和较多的抗癫痫药物与 NCI 相关。初步研究结果表明，可能需要在 TLT+ 和非肿瘤性癫痫人群中分别建立认知结果的预后模型。

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Neurocognition in Pediatric Temporal Lobe Tumor-Related Epilepsy.

Tumor-related epilepsy is a common and understudied neurological comorbidity among pediatric temporal lobe tumor patients that poses risk for neurocognitive impairment (NCI). Forty-one youth with either TLT+ (n = 23) or nonneoplastic temporal lobe epilepsy (n = 18) ages 6-20 years completed routine neuropsychological evaluations. Rates of NCI were similar across groups; however, NCI was more common in nonneoplastic participants on a task of phonemic fluency, p = .047. Younger age of seizure onset and greater number of antiseizure medications were associated with NCI among TLT+ participants only. Preliminary findings suggest separate prognostic models of cognitive outcomes between TLT+ and nonneoplastic epilepsy populations may be needed.

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来源期刊

Developmental Neuropsychology 医学-心理学

CiteScore

2.80

自引率

6.70%

发文量

审稿时长

>12 weeks

期刊介绍： Devoted to exploring relationships between brain and behavior across the life span, Developmental Neuropsychology publishes scholarly papers on the appearance and development of behavioral functions, such as language, perception, and social, motivational and cognitive processes as they relate to brain functions and structures. Appropriate subjects include studies of changes in cognitive function—brain structure relationships across a time period, early cognitive behaviors in normal and brain-damaged children, plasticity and recovery of function after early brain damage, the development of complex cognitive and motor skills, and specific and nonspecific disturbances, such as learning disabilities, mental retardation, schizophrenia, stuttering, and developmental aphasia. In the gerontologic areas, relevant subjects include neuropsychological analyses of normal age-related changes in brain and behavioral functions, such as sensory, motor, cognitive, and adaptive abilities; studies of age-related diseases of the nervous system; and recovery of function in later life. Empirical studies, research reviews, case reports, critical commentaries, and book reviews are featured in each issue. By publishing both basic and clinical studies of the developing and aging brain, the journal encourages additional scholarly work that advances understanding of the field of lifespan developmental neuropsychology.