V. L. Vaks, A. A. Aizenshtadt, V. A. Anfertev, E. G. Domracheva, M. B. Chernyaeva, P. P. Mokeeva, D. V. Kryazhev
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Application of High-Resolution Terahertz Spectroscopy for Studying Biofilms Typical of ENT Pathologies
A biofilm as the main type of existence of bacterial associations, which has its spatial and metabolic structure, is formed on the mucosa in a human body. The study of the main pathobionts and their abilities for biofilm formation at chronic adenotonsillitis, with the identification of tissue metabolites and a comparative analysis confirming the effect of the pathogen, is carried out using the methods of high-resolution terahertz gas spectroscopy. The biofilms formed by Staphylococcus aureus, Streptococcus pyogenes, Klebsiella pneumoniae, and Enterobacter coli are studied to reveal products of their thermal decomposition and identify the set which is characteristic of microorganisms. The sets of thermal-decomposition products of biofilms for different microorganisms demonstrate the composition difference, which can be used to create metabolic profiles of bacteria and the medical diagnostics methods.
期刊介绍：
Radiophysics and Quantum Electronics contains the most recent and best Russian research on topics such as:
Radio astronomy;
Plasma astrophysics;
Ionospheric, atmospheric and oceanic physics;
Radiowave propagation;
Quantum radiophysics;
Pphysics of oscillations and waves;
Physics of plasmas;
Statistical radiophysics;
Electrodynamics;
Vacuum and plasma electronics;
Acoustics;
Solid-state electronics.
Radiophysics and Quantum Electronics is a translation of the Russian journal Izvestiya VUZ. Radiofizika, published by the Radiophysical Research Institute and N.I. Lobachevsky State University at Nizhnii Novgorod, Russia. The Russian volume-year is published in English beginning in April.
All articles are peer-reviewed.
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