在脚板上涂抹外用类固醇后,造影术后出现头晕:随机对照试验

IF 1.6 4区 医学 Q2 OTORHINOLARYNGOLOGY
Behrouz Barati MD, Arvin Shahzamani MD, Ali Goljanian Tabrizi MD, Mahboobe Asadi MD
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引用次数: 0

摘要

背景 耳硬化症的特征是耳廓内异常的骨质增生。目前,镫骨切除术是治疗耳硬化症的常用方法。目前,术后头晕与镫骨切除术有关。1981 年,鼓室内地塞米松被用于治疗耳鸣和急性感音神经性听力损失等内耳疾病。然而,在镫骨切开术期间,中耳局部使用类固醇治疗的效果和安全性还存在很多不确定性。在本研究中,我们评估了镫骨切除术期间局部类固醇治疗对术后头晕的影响。 方法 将符合定型切除术条件的耳硬化症患者随机分为两组,一组使用地塞米松,另一组使用安慰剂。观察并记录相关频率的听力和鼓室测量结果。头晕障碍量表用于量化患者对头晕和平衡问题的感知。出院时和手术后 4 个月再次进行听力和头晕评估。 结果 该研究包括 72 名接受镫骨手术的耳硬化症患者。出院时,与安慰剂组相比,干预组的头晕发生率明显降低。然而,在术后 4 个月的随访中,两组患者的头晕发生率均有所下降,但无明显差异。两组的听力水平也无明显差异。有趣的是,与对照组相比,干预组术后对全身性抗头晕药物的需求明显减少。 结论 在镫骨切开术中局部使用地塞米松能有效减轻出院时的头晕症状,并减少术后服用抗头晕药物的需求。 证据等级 2。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Post-stapedotomy dizziness after applying topical steroid on footplate: A randomized controlled trial

Post-stapedotomy dizziness after applying topical steroid on footplate: A randomized controlled trial

Background

Otosclerosis is characterized by abnormal bone growth in the otie capsule. Nowadays, stapedotomy is commonly used for otosclerosis treatment. Currently, postoperative dizziness has been associated with stapedotomy. In 1981, intratympanic dexamethasone was utilized to manage inner ear disorders like tinnitus and acute sensorineural hearing loss. However, there is much uncertainty regarding the effect and safety of topical steroid therapy in the middle ear during stapedotomy. In the present study, we assessed the effect of topical steroid therapy during stapedotomy on postoperative dizziness.

Methods

Otosclerosis patients eligible for stapedotomy were randomly divided into two groups based on dexamethasone administration or placebo. Audiometric and tympanometry results were observed and recorded for the involved frequencies. The Dizziness Handicap Inventory was used to quantify patient perceptions of dizziness and balance issues. Audiometry and dizziness assessments were repeated at discharge and 4 months after the operation.

Results

The study comprised 72 otosclerosis patients undergoing stapedotomy. At discharge, the intervention group showed a significant reduction in the incidence of dizziness compared to the placebo group. However, in the 4-month follow-up after the operation, both groups experienced a decrease in dizziness incidence, with no significant difference between them. There was also no significant difference in audiometric levels between the two groups. Interestingly, the intervention group had a significantly lower need for systemic anti-dizziness drugs after surgery compared to the control group.

Conclusion

Topical dexamethasone during stapedotomy effectively minimizes dizziness at discharge and reduces the need for postoperative anti-dizziness medication.

Level of evidence

2.

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来源期刊
CiteScore
3.00
自引率
0.00%
发文量
245
审稿时长
11 weeks
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