肌球蛋白发生突变，无法克服其抑制作用。
IF 3.3
2区 医学
Q1 PHYSIOLOGY
引用次数: 0
摘要
JGP 研究（Duno-Miranda 等人，https://doi.org/10.1085/jgp.202313522）显示，与扩张型心肌病有关的一种突变可使 β-心肌酶稳定在自身抑制、超松弛状态。本文章由计算机程序翻译，如有差异，请以英文原文为准。
A mutation that prevents myosin from overcoming its inhibitions.
JGP study (Duno-Miranda et al. https://doi.org/10.1085/jgp.202313522) shows that a mutation linked to dilated cardiomyopathy stabilizes β-cardiac myosin in its autoinhibited, super-relaxed state.
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来源期刊
CiteScore
6.00
自引率
10.50%
发文量
88
审稿时长
6-12 weeks
期刊介绍：
General physiology is the study of biological mechanisms through analytical investigations, which decipher the molecular and cellular mechanisms underlying biological function at all levels of organization.
The mission of Journal of General Physiology (JGP) is to publish mechanistic and quantitative molecular and cellular physiology of the highest quality, to provide a best-in-class author experience, and to nurture future generations of independent researchers. The major emphasis is on physiological problems at the cellular and molecular level.
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