双相情感障碍的神经进展：为什么对就是错？

IF 5.9 2区医学 Q1 PSYCHIATRY

Psychological Medicine Pub Date : 2024-05-10 DOI:10.1017/S0033291724001016

Eduard Vieta

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引用次数: 0

摘要

尽管一些还原论者声称只有一种模式是正确的，但关于双相情感障碍是神经发育性疾病还是神经进行性疾病的争议依然存在。目前的诊断分类方法无助于解决这一问题，而且支持和反对这两种模式的证据也相互矛盾。但在实践中，了解到许多患者可能会出现认知和功能的进行性衰退，而这种衰退可能与发作的次数和严重程度相关，通过早期干预策略可能会取得更好的疗效。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Neuroprogression in bipolar disorder: why right is wrong.

The controversy on whether bipolar disorder is a neurodevelopmental versus a neuroprogressive illness is still around, despite some reductionistic claims that only one model is right. The current diagnostic classifications are not helpful to address this issue, and there is conflicting evidence in favor and against either model. In practice, though, understanding that many patients may show a progressive cognitive and functional decline which may be correlated with the number and severity of episodes may lead to better outcomes through early intervention strategies.

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来源期刊

Psychological Medicine 医学-精神病学

CiteScore

11.30

自引率

4.30%

发文量

711

审稿时长

3-6 weeks

期刊介绍： Now in its fifth decade of publication, Psychological Medicine is a leading international journal in the fields of psychiatry, related aspects of psychology and basic sciences. From 2014, there are 16 issues a year, each featuring original articles reporting key research being undertaken worldwide, together with shorter editorials by distinguished scholars and an important book review section. The journal''s success is clearly demonstrated by a consistently high impact factor.