在基于臂的网络荟萃分析中使用固定研究主效应。

IF 5 2区生物学 Q1 MATHEMATICAL & COMPUTATIONAL BIOLOGY

Research Synthesis Methods Pub Date : 2024-05-09 DOI:10.1002/jrsm.1721

Hans-Peter Piepho, Laurence V. Madden, Emlyn R. Williams

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引用次数: 0

摘要

网络荟萃分析（NMA）方法可分为以臂为基础的方法和以对比为基础的方法。基于研究臂的方法有多种，其中一些方法因其恢复研究间信息而不符合并发控制原则而受到批评。在此，我们指出，在基于研究臂的 NMA 中，可以通过拟合研究的固定主效应来防止研究间信息的恢复。我们还讨论了基于研究臂的 NMA 的优点。

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The use of fixed study main effects in arm-based network meta-analysis

Methods of network meta-analysis (NMA) can be classified as arm-based and contrast-based approaches. There are several arm-based approaches, and some of these have been criticized because they recover inter-study information and hence do not obey the principle of concurrent control. Here, we point out that recovery of inter-study information in arm-based NMA can be prevented by fitting a fixed main effect for studies. Advantages of arm-based NMA are discussed.

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来源期刊

Research Synthesis Methods MATHEMATICAL & COMPUTATIONAL BIOLOGYMULTID-MULTIDISCIPLINARY SCIENCES

CiteScore

16.90

自引率

3.10%

发文量

期刊介绍： Research Synthesis Methods is a reputable, peer-reviewed journal that focuses on the development and dissemination of methods for conducting systematic research synthesis. Our aim is to advance the knowledge and application of research synthesis methods across various disciplines. Our journal provides a platform for the exchange of ideas and knowledge related to designing, conducting, analyzing, interpreting, reporting, and applying research synthesis. While research synthesis is commonly practiced in the health and social sciences, our journal also welcomes contributions from other fields to enrich the methodologies employed in research synthesis across scientific disciplines. By bridging different disciplines, we aim to foster collaboration and cross-fertilization of ideas, ultimately enhancing the quality and effectiveness of research synthesis methods. Whether you are a researcher, practitioner, or stakeholder involved in research synthesis, our journal strives to offer valuable insights and practical guidance for your work.