[病人血液管理--不能忽视这项政策]。

Harefuah Pub Date : 2024-04-01
Andrei Braester, Luiza Akria, Moran Zarfati, Masad Barhoum
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引用次数: 0

摘要

导言:贫血是一种常见病,也是发病率和死亡率的一个独立风险因素,尤其是在大手术前(30-40%的患者接受大手术)或术后贫血(高达 80-90%)。根据世界卫生组织(WHO)的标准,2010 年全球贫血人口占总人口的四分之一(19 亿),而缺铁性贫血(IDA)过去是、现在仍然是全球最常见的贫血类型,占贫血总负担的一半以上。在《2016 年全球疾病负担研究》的一项系统分析中,缺铁性贫血是导致残疾年数的第四大原因,尤其是对女性而言,因此预防和治疗缺铁性贫血是一项重要的公共卫生目标。输注红细胞(RBC)是一种常见的治疗干预措施,但在临床实践中存在相当大的差异。全世界每年输注的包装红细胞(PRBC)超过 8500 万单位。输血(BT)的主要适应症是贫血,但有相当比例的红细胞输注被不适当地过度使用。对于许多不同专科的医生和临床医师来说,输血仍被视为治疗贫血的一线疗法。联合委员会和美国医学会已将 BT 列入美国五种最过度使用的治疗程序名单。限制性输血(RBT)是一项以证据为基础的政策,至少与自由输血政策同样有效,甚至更胜一筹。患者血液管理(PBM)是一种以患者为中心的系统化循证方法,并得到 RBT 的支持。本文分析了影响 PBM 实施的因素。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[PATIENT BLOOD MANAGEMENT - IT IS IMPOSSIBLE TO IGNORE THIS POLICY].

Introduction: Anemia is common and is an independent risk factor for morbidity and mortality, especially in pre- (30-40% of patients undergoing major surgery) or post-operative anemia (up to 80-90%). Using World Health Organization (WHO) criteria, in 2010 one quarter of the global population was anemic (1.9 billion people) and iron deficiency anemia (IDA( was and still remains the most common type of anemia worldwide, accounting for more than half of the total anemia burden. In a systematic analysis for the Global Burden of Disease Study 2016, IDA was the fourth leading cause of years lived with disability, particularly in women, thus highlighting prevention and treatment of IDA as a major public health goal. Red blood cells (RBC) transfusion is a common therapeutic intervention with considerable variation in clinical practice. More than 85 million units packed RBC (PRBC) are transfused annually worldwide. The principal indication for blood transfusion (BT) is anemia, yet a significant percentage of RBC transfusions are inappropriately overused. For many physicians and clinicians, across many different specialties, BT is still considered to be the first-line treatment when facing anemia. The Joint Commission along with the American Medical Association has included BT in a list of the five most overused therapeutic procedures in the United States. Restrictive blood transfusion (RBT) is an evidence-based policy, at least as effective, if not superior to the liberal policy of BT. Patient blood management (PBM) is a patient-centered systematic, evidence-based approach, supported by RBT. In this article we analyze the factors which influence the implementation of PBM.

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