对接受非小细胞肺癌手术的老年患者进行术前虚弱筛查:获得良好手术效果的必要步骤。

Expert review of respiratory medicine Pub Date : 2024-03-01 Epub Date: 2024-05-07 DOI:10.1080/17476348.2024.2349579
Radu Iacobescu, Sabina Antonela Antoniu, Alina Delia Popa, Mariana Pavel-Tanase, Teodora Alexa Stratulat
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引用次数: 0

摘要

导言非小细胞肺癌(NSCLC)是一种常见于老年人的疾病,通常处于晚期。然而,只要在术前对术后风险进行适当评估,老年肺癌患者也能从手术中获益。虚弱是衡量与年龄相关的功能受损状况的指标,也是预测死亡率和发病率的指标。然而,其作为术前标志物的重要性还没有得到很好的界定:本系统综述讨论了对 NSCLC 老年患者进行术前虚弱筛查的重要性。我们于 2023 年 6 月在 MEDLINE 数据库中进行了文献检索,并保留了 2000 年至 2023 年间发表的有关虚弱或 NSCLC 术前评估的相关研究,并在本综述中进行了讨论:专家意见:在现有的各类虚弱评估方法中,老年评估方法似乎是最合适的,但它们无法完全捕捉到 "手术 "虚弱;因此,应开发其他工具并在 NSCLC 中进行验证。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Preoperative frailty screening in elderly patients with non-small cell lung cancer surgery: an essential step for a good surgical outcome.

Introduction: Non-small cell lung cancer (NSCLC) is a disease commonly diagnosed in the elderly, often in advanced stages. However, elderly patients with lung cancer can benefit from surgery, provided that postoperative risks are assessed appropriately before surgery. Frailty is a measure of age-related impaired functional status and a predictor of mortality and morbidity. However, its importance as a preoperative marker is not well defined.

Areas covered: This systematic review discusses the importance of preoperative frailty screening in elderly patients with NSCLC. A literature search was performed on the MEDLINE database in June 2023, and relevant studies on frailty or preoperative assessment of NSCLC which were published between 2000 and 2023 were retained and discussed in this review.

Expert opinion: Among the types of existing methods used to assess frailty those on the geriatric assessment seem to be the most appropriate; however, they are unable to fully capture the 'surgical' frailty; thus, other instruments should be developed and validated in NSCLC.

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