神经营养性角膜病:一般特征和新疗法

IF 5.1 2区 医学 Q1 OPHTHALMOLOGY
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引用次数: 0

摘要

神经营养性角膜病是一种不常见的退行性角膜疾病,其特点是角膜感觉神经受损,从而形成上皮缺损和不愈合的角膜溃疡。目前有多种治疗方法可用于稳定病情发展、改善患者健康状况和预防视力丧失。对于符合条件的患者,药物和手术神经再支配疗法已成为先驱疗法,有望实现更好的治疗效果。本文对该疾病进行了全面综述,为眼科医生提供了有关发病机制、诊断、治疗方案和针对病理生理途径的新型疗法的最新信息。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Neurotrophic keratopathy: General features and new therapies.

Neurotrophic keratopathy is an uncommon degenerative corneal disorder characterized by compromised corneal sensory innervation resulting in the formation of epithelial defects and nonhealing corneal ulcers. Various treatment modalities are available to stabilize disease progression, improve patient well-being, and prevent vision loss. For eligible patients, medical and surgical reinnervation have emerged as pioneering therapies, holding promise for better management. We present a comprehensive review of the disorder, providing an update relevant to ophthalmologists on pathogenesis, diagnosis, treatment options, and novel therapies targeting pathophysiological pathways.

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来源期刊
Survey of ophthalmology
Survey of ophthalmology 医学-眼科学
CiteScore
10.30
自引率
2.00%
发文量
138
审稿时长
14.8 weeks
期刊介绍: Survey of Ophthalmology is a clinically oriented review journal designed to keep ophthalmologists up to date. Comprehensive major review articles, written by experts and stringently refereed, integrate the literature on subjects selected for their clinical importance. Survey also includes feature articles, section reviews, book reviews, and abstracts.
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