一例无甲状腺结节的楔形膜甲状腺癌

JCEM case reports Pub Date : 2024-04-18 eCollection Date: 2024-04-01 DOI:10.1210/jcemcr/luae062
Angela Rao, Leor Needleman, M Lauren Lalakea, Emory Hsu
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引用次数: 0

摘要

楔形膜甲状腺癌是一种罕见的甲状腺癌。它与家族性腺瘤性息肉病(FAP)密切相关,FAP是一种遗传性基因疾病,易导致结肠和直肠出现大量息肉。我们描述了一例年轻女性患者的病例,她出现甲状腺肿大,但超声检查未发现甲状腺结节或肿块,甲状腺全切除术后发现她患有楔形甲状腺癌。这一诊断结果导致了基因检测和FAP综合征的诊断。我们的研究表明,这种罕见的甲状腺癌在超声检查中可能没有可疑的发现,但在诊断FAP综合征时却是一个重要的先兆。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A Case of Cribriform-Morular Thyroid Carcinoma Presenting Without Thyroid Nodule.

Cribriform-morular thyroid carcinoma is a rare type of thyroid cancer. It has a strong association with familial adenomatous polyposis (FAP), a hereditary genetic disorder that predisposes individuals to the development of numerous polyps in the colon and rectum. We describe the case of a young female patient who presented with an enlarging goiter, notably without detectable thyroid nodules or masses on ultrasound, who after total thyroidectomy was found to have cribriform-morular thyroid carcinoma. This diagnosis led to genetic testing and diagnosis of FAP syndrome. We demonstrate that this rare thyroid carcinoma may present with nonsuspicious findings on sonographic evaluation while being a valuable harbinger in the diagnosis of FAP syndrome.

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