非典型孤立性惊厥：两份病例报告和一篇小型综述。

IF 0.6 4区医学 Q4 CLINICAL NEUROLOGY

Neurocase Pub Date : 2023-06-01 Epub Date: 2024-04-27 DOI:10.1080/13554794.2024.2347606

Vinay Mandagere, Dane Rayment

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引用次数: 0

摘要

惊厥是指肌肉张力突然丧失，通常由大笑或兴奋等情绪引起。惊厥是 1 型嗜睡症（NT1）的基本诊断特征之一。我们描述了两例结果不同的孤立性惊厥病例，强调了诊断和预后方面的挑战。关于它是一种合法的独立诊断，还是嗜睡症的早期预警信号，目前存在相互矛盾的文献。我们的病例不符合当前的嗜睡症诊断标准，但仍具有一些临床或实验室特征。这些模棱两可的病例对嗜睡症和惊厥之间的机理关系提出了质疑。

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Atypical isolated cataplexy: two case reports and a mini-review.

Cataplexy is the sudden loss of muscle tone often provoked by emotion such as laughter or excitement. Cataplexy is one of the essential diagnostic features of Narcolepsy type 1 (NT1). We describe two cases of isolated cataplexy with different outcomes, highlighting the diagnostic and prognostic challenges. There is conflicting literature as to whether it is a legitimate standalone diagnosis or an early warning sign of narcolepsy. Our cases do not fit with current diagnostic criteria for narcolepsy, yet still share some clinical or laboratory features. These ambiguous cases question what the mechanistic relationship between narcolepsy and cataplexy may be.

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来源期刊

Neurocase 医学-精神病学

CiteScore

1.40

自引率

12.50%

发文量

审稿时长

6-12 weeks

期刊介绍： Neurocase is a rapid response journal of case studies and innovative group studies in neuropsychology, neuropsychiatry and behavioral neurology that speak to the neural basis of cognition. Four types of manuscript are considered for publication: single case investigations that bear directly on issues of relevance to theoretical issues or brain-behavior relationships; group studies of subjects with brain dysfunction that address issues relevant to the understanding of human cognition; reviews of important topics in the domains of neuropsychology, neuropsychiatry and behavioral neurology; and brief reports (up to 2500 words) that replicate previous reports dealing with issues of considerable significance. Of particular interest are investigations that include precise anatomical localization of lesions or neural activity via imaging or other techniques, as well as studies of patients with neurodegenerative diseases, since these diseases are becoming more common as our population ages. Topic reviews are included in most issues.