COVID-19大流行的第二、第三和第四波对头颈癌候诊时间的影响：法国一家专家中心的回顾性研究。

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2024-09-01 DOI:10.1016/j.anorl.2024.04.001

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引用次数: 0

摘要

背景：头颈部癌症的治疗延误是一个重大问题，会影响患者的生存。COVID-19（冠状病毒病 2019）大流行在全球范围内呈波浪式发展，导致某些癌症的诊断和治疗延误。本研究的主要目的是分析我们中心在连续三次大流行中等待时间是否发生了变化：这是一项单中心回顾性研究，研究对象是首次诊断为头颈部癌症的患者。研究将第二、第三和第四波的三组患者与大流行前的对照组进行比较。研究数据包括首次就诊与肿瘤委员会会议（C1-TB）之间的中位时间，以及肿瘤委员会会议与治疗（TB-T）之间的中位时间。显著性阈值设定为 PResults：对照组有 96 名患者，"2-3-4 波 "组有 154 名患者。C1-TB间隔（分别为35天和26天，P=0.046）或TB-T间隔（分别为27天和28天，P=0.723）没有增加：结论：在本中心，COVID-19 的第二、第三和第四波期间，首次就诊与肿瘤委员会会议之间的间隔以及肿瘤委员会会议与治疗之间的间隔没有增加。

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Impact of the 2nd, 3rd and 4th waves of the COVID-19 pandemic on wait times in head and neck cancer: A retrospective study in a French expert center

Background

Treatment delay in head and neck cancer is a major problem, with impact on survival. The COVID-19 (coronavirus disease 2019) pandemic, evolving in waves around the world, caused diagnostic and therapeutic delays in certain cancers. The main objective of the present study was to analyze whether there was a change in wait times during three successive waves in our center.

Method

This was a single-center retrospective study of patients with a first diagnosis of head and neck cancer. Three groups, corresponding to waves 2, 3 and 4, were compared to a control group corresponding to a pre-pandemic period. Study data comprised median times between first consultation and tumor board meeting (C1-TB) and between tumor board meeting and treatment (TB-T). The significance threshold was set at P < 0.005.

Results

Ninety-six patients were included in the control group, and 154 in the “waves 2-3-4” group. There was no increase in C1-TB interval (respectively 35 and 26 days, P = 0.046) or TB-T interval (respectively 27 and 28 days, P = 0.723).

Conclusion

Intervals between first consultation and tumor board meeting and between tumor board meeting and treatment did not increase during the 2nd, 3rd and 4th waves of COVID-19 in our center.

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.