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引用次数: 0
摘要
目的：本综述旨在评估有关哺乳史对阿尔茨海默病晚期发展影响的现有证据。研究方法作者检索了 PubMed、Cumulative Index to Nursing and Allied Health Literature、Scopus 和 Excerpta Medica dataBASE 等电子数据库，并使用 "阿尔茨海默病、痴呆症 "和 "母乳喂养、哺乳 "等检索词进行了逆向参考文献检索。作者通过应用纳入和排除标准以及阅读标题、摘要或记录全文来选择相关记录。结果：共鉴定了 400 篇文章，并对符合纳入标准的 10 篇文章进行了分析。作者按照《系统综述和元分析首选报告项目》指南提取数据，并根据 Melnyk 和 Fineout-Overholt 的方法对证据等级进行评分。数据按照母乳喂养持续时间、曾经哺乳以及母乳喂养的间接影响等主题进行整理。结论母乳喂养可能会对哺乳者的神经产生保护作用，并降低晚年患阿尔茨海默氏症的风险。然而，未来的研究有必要确定这种关联的普遍性。
Effects of a Person's Lactation History on Later-Life Development of Alzheimer's Disease: An Integrative Review.
Objective: The purpose of this integrative review is to assess the existing evidence regarding the effects of a person's lactation history on later-life development of Alzheimer's disease. Methods: The authors searched the electronic databases PubMed, Cumulative Index to Nursing and Allied Health Literature, Scopus, and Excerpta Medica dataBASE, and performed backward reference searches using search terms such as, "Alzheimer's disease, dementia," and "breastfeeding, lactation." Authors selected relevant records through the application of inclusion and exclusion criteria and reading the titles, abstracts, or records in full. Results: In total, 400 articles were identified, and 10 articles meeting inclusion criteria were analyzed. Authors extracted data following Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines and scored levels of evidence according to Melnyk and Fineout-Overholt. Data were organized according to themes of breastfeeding duration, ever having breastfed, and indirect effects of breastfeeding. Conclusions: Breastfeeding may have neuroprotective effects for the lactating person and reduce the risk of later-life development of Alzheimer's disease. However, future research is necessary to determine the generalizability of this association.
期刊介绍：
Breastfeeding Medicine provides unparalleled peer-reviewed research, protocols, and clinical applications to ensure optimal care for mother and infant. The Journal answers the growing demand for evidence-based research and explores the immediate and long-term outcomes of breastfeeding, including its epidemiologic, physiologic, and psychological benefits. It is the exclusive source of the Academy of Breastfeeding Medicine protocols.
Breastfeeding Medicine coverage includes:
Breastfeeding recommendations and protocols
Health consequences of artificial feeding
Physiology of lactation and biochemistry of breast milk
Optimal nutrition for the breastfeeding mother
Breastfeeding indications and contraindications
Managing breastfeeding discomfort, pain, and other complications
Breastfeeding the premature or sick infant
Breastfeeding in the chronically ill mother
Management of the breastfeeding mother on medication
Infectious disease transmission through breast milk and breastfeeding
The collection and storage of human milk and human milk banking
Measuring the impact of being a “baby-friendly” hospital
Cultural competence and cultural sensitivity
International public health issues including social and economic issues.
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